K. Gairola, Shriya Gururani, Ravendra Kumar, O. Prakash, S. Agarwal, S. Dubey
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Phytochemical composition, antioxidant, and anti-inflammatory activities of essential oil of Acmella uliginosa (Sw.) Cass. grown in North India Terai region of Uttarakhand
The plant Acmella uliginosa (Sw.) Cass. belonging to family Asteraceae was subjected to hydro distillation for essential oil extraction and was chemically analyzed by GC/MS for its phytochemical composition. Thirty-five compounds were identified comprising 88.1% of total essential oil composition. Limonene (12.2%) along with sesquisabinene isomer (7.3%) and caryophyllene oxide (5.9%) were the prominent compounds of the essential oil. In-vitro antioxidant activity of essential oil was investigated by DPPH free radical scavenging activity and metal chelating activity having IC50 value of 326.77 ± 5.34 μL and 14.853 ± 0.106 μL respectively whereas reducing power activity having RP50 value of 14.011 ± 0.0446 μL. The essential oil exhibited potent anti-inflammatory activity with IB50 value of 5.629 ± 0.0311 μL compared to standard Diclofenac sodium salt having IB50 value of 23.693 ± 0.306 μg/mL. The essential oil displayed exceedingly marked anti-inflammatory as well as antioxidant activities as compared to standard marketed drugs.
期刊介绍：
Town Planning Review has been one of the world"s leading journals of urban and regional planning since its foundation in 1910. With an extensive international readership, TPR is a well established urban and regional planning journal, providing a principal forum for communication between researchers and students, policy analysts and practitioners. To mark TPR’s centenary in 2010, it is proposed to publish a series of ‘Centenary Papers’ -- review papers that record and reflect on the state of the art in a range of topics in the general field of town and regional planning.
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