孕妇妊娠期感染新冠肺炎的研究报告

F. Zare, S. Daliri, Sakineh Kolahdouzan, M. Rohani-Rasaf
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引用次数: 0

摘要

本案例研究包括三名在2020年3月28日至5月13日期间怀孕或分娩期间被诊断患有新冠肺炎的孕妇。所有病例均通过咽逆转录聚合酶链反应(RT-PCR)阳性检测得到证实,一例病例除通过(RT-PCR)外还通过计算机断层扫描(CT扫描)得到证实。临床和实验室信息是从怀孕和分娩期间的医院记录中提取的。研究了妊娠期间和新生儿出生后的不良反应,以及阳性孕妇向新生儿垂直传播的可能性。在三名感染新冠肺炎的女性中,一名患者在分娩前两周被确诊,两名患者在生产和住院期间被确诊。没有观察到包括先兆子痫、妊娠期高血压、妊娠期羊膜囊破裂和早产在内的不良反应,但其中一名患者患有宫内胎儿死亡(IUFD)。在这项研究中,根据医院观察,新冠肺炎感染孕妇未观察到不良妊娠结局。阴道分娩或剖宫产后及妊娠期间未观察到垂直传播。由于病毒对社会中不同人群的影响因其个体特征而异,我们在这项针对孕妇的研究中得出的结论也受到这些个体差异的影响,这需要在该领域进行更多样本的进一步研究。
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Study of Pregnant Women Infected with COVID-19 During Pregnancy: A Case Report
This case study includes three pregnant women with COVID-19 diagnosed during pregnancy or delivery between March 28 and May 13, 2020. All cases were confirmed by a positive pharyngeal reverse transcription polymerase chain reaction (RT-PCR) test and one case by computed tomography scan (CT Scan) in addition to the (RT-PCR). Clinical and laboratory information was extracted from hospital records during pregnancy and delivery. The adverse effects during pregnancy and after the birth of the newborn, the possibility of vertical transmission from positive pregnant mothers to the neonates were investigated.Of the three women with COVID-19 infection, one patient was diagnosed two weeks before delivery and two were diagnosed during delivery and hospitalization. No adverse effects including preeclampsia, gestational hypertension, rupture of the amniotic sac during pregnancy and premature delivery were observed but one of the patients suffered from intrauterine fetal death (IUFD). in this study, adverse pregnancy outcome was not observed in pregnant women with Covid-19 infection based on hospital observations. No vertical transmission was observed following vaginal delivery or cesarean section and during pregnancy. As the effect of the virus on different people in society varies according to their individual characteristics, our conclusion in this study on pregnant women is also affected by these individual differences, which requires further studies in this field with more samples.
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