局部晚期宫颈癌放化疗治疗:特殊复发1例报告

Luca Guaraldi, P. Pastina, P. Tini, M. Crociani, S. Marsili, V. Nardone
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引用次数: 0

摘要

宫颈腺癌的治疗通常采用同步化疗和外束放疗(EBRT),最后进行近距离放疗,可提供良好的肿瘤控制率,尽管约三分之一的患者可进一步复发。最常见的复发部位是骨盆和主动脉旁淋巴结,很少有患者有单一的转移沉积。在这方面,复发的精确定义和最佳治疗策略仍有待明确界定,目前尚无治疗少转移性宫颈癌患者的指南。我们报告了一例81岁的IIB期子宫颈腺癌患者,并成功地进行了明确目的的同步放化疗。六个月后,她出现了一个孤立的腹部结节,她接受了切除和化疗。目前,3年后没有局部复发或远处转移的迹象。在报告的病例中,使用不同的策略(放疗,化疗和手术),以及正确的选择和不同方法的时机,为患者提供了很大的好处。对复发性宫颈癌患者进行手术和化疗是安全的,即使对非典型的老年患者也是如此
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Locally advanced cervical cancer treated with chemo-radiotherapy: a case report of a particular recurrence
Adenocarcinoma of uterine cervix is usually treated with concurrent chemotherapy and external beam radiotherapy (EBRT), eventually followed by brachytherapy that can provide a good tumor control rate, although approximately one-third of the patients can develop further recurrence. The most common recurrence sites are the pelvis and the para-aortic nodes, with few patients having a single metastatic deposit. In this regard, precise definitions of recurrences and optimal treatment strategies are still to be clearly defined and currently there are no guidelines for the treatment of patients with oligometastatic cervical cancer. We present a case of an 81 years old patient with Stage IIB adenocarcinoma of uterine cervix, that was successfully treated with concurrent chemoradiotherapy with definitive intent. Six months later, she developed a solitary abdominal nodule for which she underwent resection followed by chemotherapy. At the present time there are no signs of local recurrence or distant metastasis after 3 years. In the case reported, the use of different strategies (radiotherapy, chemotherapy and surgery), as well as the correct choice and the timing of the different approaches has provided a great benefit for the patient. The use of surgery and chemotherapy in patients with recurrent cervical cancer is safe even in older patients with atypical
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