严重新冠肺炎呼吸道疾病后重症监护综合征和功能结果:卡塔尔康复医院的经验

K. Narayanankutty, S. Ullah, Saquib Hanif, Mohamed Missaoui, R. Saad
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摘要

目的:本研究旨在观察新冠肺炎重症监护后综合征(PICS)患者冠状病毒病(COVID)康复后的功能结果。方法:我们报告了13例重症新冠肺炎肺炎患者,他们需要长期入住重症监护室(ICU),后来在2020年7月和8月期间因PICS和功能性残疾入住我们的康复机构。所有这些患者都接受了多学科康复计划,是第一批成功出院的患者。结果:在13名患者中,11名为男性,2名为女性,年龄在34-64岁之间。13名患者中有10人至少患有一种慢性疾病,如糖尿病、系统性高血压、血脂异常、阻塞性气道疾病和冠状动脉疾病,其中7人患有一种以上疾病。他们都没有任何已知的神经精神疾病。他们都患有严重肺炎,需要机械通气12至30天,平均ICU住院时间为36天(21至54天)。康复入院时最常见的损伤是运动耐受性受损,在改良医学研究委员会(mMRC)呼吸困难量表和40步步行测试中得分较低,以及重症监护室获得性虚弱,医学研究委员会的总分在30-46分(满分60分)之间。13名患者中有8名患有神经电诊断测试诊断的危重症肌病和/或神经病变。康复患者的平均住院时间为36天,范围为18-65天。结论:早期多学科康复对新冠肺炎幸存者的功能结果具有潜在的益处。需要在这一领域进行更多的研究,以进一步评估不同康复干预措施的益处、强度、持续时间和长期益处,并为未来应对类似情况制定指导方针。
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Postintensive care syndrome after severe COVID-19 respiratory illness and functional outcomes: Experience from the rehabilitation hospital in Qatar
Objective: This study aimed to observe functional outcomes post coronavirus disease (COVID) rehabilitation in COVID-19 patients with postintensive care syndrome (PICS). Methods: We present 13 cases of severe COVID-19 pneumonia who required prolonged intensive care unit (ICU) stay, and were later admitted to our rehabilitation institute with features of PICS and functional disability, during the months of July and August 2020. All these patients underwent a multidisciplinary rehabilitation program and are the first group of patients successfully discharged to the community. Results: Among 13 patients presented, 11 were male patients and 2 were female, in the age range 34–64 years. Ten out of 13 patients had at least one chronic illness such as diabetes mellitus, systemic hypertension, dyslipidemia, obstructive airway disease, and coronary artery disease, and seven among them had more than one illness. None of them had any known neuropsychiatric illnesses. All of them had severe pneumonia which required mechanical ventilation from 12 to 30 days and an average length of ICU stay of 36 days (Range 21–54 days). The most common impairments on rehabilitation admission were impaired exercise tolerance with poor scores in Modified Medical Research Council (mMRC) dyspnea scale and desaturation on 40-step walking test, as well as significant ICU acquired weakness with a Medical Research Council (MRC) sum score in the range of 30–46 out of 60. Eight out of 13 patients had critical illness myopathy and/or neuropathy diagnosed with neuro-electrodiagnostic testing. The average length of stay for the patients in rehabilitation was 36 days, with a range of 18–65 days. Conclusion: Early multidisciplinary rehabilitation has got a potential benefit in the functional outcome of COVID-19 survivors. More studies are required in this area to further evaluate the benefits of different rehabilitation interventions, their intensity, duration, long-term benefits, and to create guidelines for addressing similar situations in the future.
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