2014-2017年Ahvaz Razi医院铁中毒患者症状患病率分析

A. Rahmani, Shahrzad Molavinia, Fatemeh Boustani
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引用次数: 0

摘要

背景:铁是正常细胞代谢的重要元素,但过量的铁具有很强的细胞毒性,甚至致命。铁中毒是世界上多次发生的灾难。患者的临床体征包括胃肠道症状、短期相对稳定、心源性休克、肝功能衰竭和胃肠道瘢痕形成。铁片对孩子们特别有吸引力,因为它们类似于糖果。铁过量的成年人通常是企图自杀。方法:本研究是一项基于医院信息的描述性分析研究,对2014-2017年在Razi医院(伊朗西南部中毒治疗转诊医疗机构)入院的铁中毒患者进行分析。将患者信息提取并插入问询表中,并通过SPSS软件对数据进行分析。结果:本研究共纳入52例患者,其中女性占94.2%。5名(9.6%)妇女怀孕。其中年龄在15-25岁之间的占69.2%。恶心和呕吐(50%)是两种最常见的副作用。5例(9.6%)患者接受去铁胺治疗。所有接受去铁胺治疗的患者,症状均在6小时内出现。大多数患者住院时间为6-24小时。25%的患者同时服用维生素和铁。3例(5.8%)患者血清铁水平高于300µg/dL。根据这项研究,报告了1例患者的死亡。结论:本研究以人口统计学和临床特征为基础,调查了铁中毒的发生率。考虑到铁中毒在年轻人群中最为普遍(96.2%自杀),更多的心理和社会问题研究对于预防行为至关重要。
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Prevalence of symptoms in patients poisoned with iron in Ahvaz Razi Hospital in 2014-2017
Background: Iron is an important element for normal cell metabolism, but in excess amounts is quite cytotoxic, and even deadly. Iron poisoning is a calamity repeated many times in the world. The clinical signs of the patients include gastrointestinal symptoms, a short period of relative stability, Cardiogenic shock, liver failure, and scarring of the gastrointestinal tract. Iron tablets are specifically tempting to children because they are similar to candy. Iron overdose in adults is usually to attempt suicide. Methods: The present study is a descriptive-analytic study based on hospital information, that was conducted among the patients affected with iron poisoning admitted to Razi hospital (a referral medical setting for poisoning treatment in southwest Iran) during 2014-2017. Patient information has been extracted and inserted in the inquiry form and data were analyzed by SPSS software. Results: In this study, 52 patients (94.2% female) were studied. 5 (9.6%) of women were pregnant.  The majority of them (69.2%) were between 15-25 years of age. Nausea and vomiting (50%) are two of the most common side effects. 5 patients (9.6%) received deferoxamine. All Patients who received deferoxamine, symptoms had less than 6 hours of onset. Most patients were hospitalized between 6-24 hours. 25% of patients took vitamins simultaneously with iron. The Serum level of iron in 3 patients (5.8%) was above 300 µg/dL. Based on this research, mortality was reported in one patient. Conclusion: In this study, the prevalence of iron poisoning was examined based on demographic and clinical characteristics. Considering the most prevalent iron poisoning in the young age group (96.2% suicides), more research in the psychological and social problems is critical for preventative behaviors.
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期刊介绍: Asia Pacific Journal of Medical Toxicology (APJMT) aims to expand the knowledge of medical toxicology and tries to provide reliable information in this field for medical and healthcare professionals. APJMT mainly focuses on research related to medical toxicology issues in the Asia Pacific region and publishes articles on clinical and epidemiological aspects of toxicology, poisonings emergency care, addiction, drug interactions and adverse effects. The journal accepts and welcomes high quality papers in the form of original articles and rarely review articles, case reports and scientific letters relevant to medical practice in toxicology.
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