围手术期目标导向治疗的现状

J. Zatloukal, J. Pouska, J. Beneš
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引用次数: 2

摘要

高风险手术通常伴随着并发症的增加和更高的死亡率。接受此类手术的患者心血管储备通常较低,限制了他们维持足够器官灌注的能力。这会使器官面临灌注不足、功能丧失甚至衰竭的风险。围手术期目标导向治疗可以改善中高危手术患者的术后预后。根据目前的证据,它似乎与缩短术后住院时间、并发症数量甚至可能死亡率有关。在接下来的叙述性回顾中,我们讨论围手术期目标导向治疗的贡献,以及它的局限性和可能的未来前景。
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Perioperative goal directed therapy—current view
High-risk surgery is frequently associated with increased number of complications and higher mortality. Cardiovascular reserves of patients undergoing such procedures are frequently low, limiting their ability to sustain adequate organ perfusion. This puts the organs into the risk of hypoperfusion with loss of function and even failure. Perioperative goal directed therapy is can improve postoperative outcome of intermediate-to-high-risk surgical patients. Based on current evidence it seems to be associated with decreased postoperative length of stay, number of complications and possibly even mortality. In following narrative review, we discuss the contribution of perioperative goal directed therapy as well as its limits and possible future perspectives.
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