副球孢子菌病1例

Nancy Alfieri Nunes, Ana Maria Pires Soubhia, Gabriela Lopes dos Santos, Leonardo Ferreira de Toledo Piza Lopes
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摘要

副球孢子菌病是一种累及肺和颊粘膜的全身性真菌疾病。目的:简要的文献调查和临床病例报告。病例报告:一名48岁男性患者,前吸烟者、酗酒者和吸毒者,因口腔周围和口腔内溃疡病变,症状疼痛,体重减轻,严重咳嗽而就诊于林斯牙科学校。临床评估疑似副球孢子菌病,并进行补充试验,包括活检巴西利亚副球孢子菌酵母菌形式的证据。辅助检查和活检确定为副球蕈菌病,原发肺部受累,继发颊粘膜受累,在30天内接受抗真菌治疗,效果良好。结论:口腔外科医生必须知道如何诊断和治疗累及口腔的全身性疾病,如副球孢子菌病,包括多学科方法,并定期保存患者,因为病变可能因临床症状恶化、耐药性甚至患者对治疗和药物不良反应的疏忽而复发。关键词:副球孢子菌病;真菌病;肺病;口腔疾病
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Paracoccidioidomycosis: Report Case
Paracoccidioidomycosis is a fungal systemic disease with involvement of the lung and buccal mucosa. Objective: A brief bibliographic survey and clinical case report. Case report: A 48-year-old male patient, former smoker, alcoholic and drug user attended the Stomatology Service Lins School of Dentistry with ulcerated lesions in the perioral and intraoral region, with painful symptomatology, weight loss, and severe cough. It was clinically evaluated with suspected paracoccidioidomycosis and underwent complementary tests, including biopsy for evidence of the yeast form of Paracoccidioides brasiliensis. Complementary exams and biopsy were conclusive for paracoccidiodoimycosis, with primary pulmonary involvement and secondary buccal mucosa involvement, being submitted to antifungal treatment with excellent result in thirty days. Conclusion: The dental surgeon must know to diagnose and treat systemic diseases with oral involvement, such as paracoccidioidomycosis, including in a multidisciplinary way, with periodic proservation of the patient, since the lesions may recur due to exacerbation of the clinical picture, drug resistance or even negligence of the patient regarding treatment and adverse drug effects. Key words: Paracocidioidomycosis; Mycoses; Pneumopathies; Oral Diseases
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