“重入”扭曲相准线性层中DNA结构的无序性

IF 0.3 Q4 CRYSTALLOGRAPHY Liquid Crystals and their Application Pub Date : 2021-06-29 DOI:10.18083/lcappl.2021.2.54
Y. Yevdokimov, S. Skuridin, S. Semenov, V. Salyanov, E. Kats
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引用次数: 0

摘要

比较了在含有聚乙二醇的溶液中形成的具有“凹入”胆甾醇结构的双链(ds)DNA分散颗粒的CD光谱。溶剂的高渗透压导致密集堆积的DNA分子及其二级结构的改变,以及分散颗粒的准向列层中分子的无序。在这些条件下,不可能通过特定的交联(纳米桥)连接相邻的ds-DNA分子。
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Disorder of DNA Structure in Quasinematic Layers of “Re-entrant” Twisted Phases
The CD spectra of double-stranded (ds) DNA dispersion particles with the “re-entrant” cholesteric structures formed in poly(ethyleneglycol)-containing solutions are compared. The high osmotic pressure of the solvent results in the dense packing DNA molecules and alteration of their secondary structure as well as a disorder of molecules in quasinematic layers of dispersion particles. Under these conditions, it is impossible to connect the adjacent ds DNA molecules by specific cross-links (nanobridges).
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来源期刊
CiteScore
1.30
自引率
40.00%
发文量
30
期刊介绍: The Journal presents the following main directions of creation/construction, study and application of self-assembled materials: SYNTHESIS, STRUCTURE, PROPERTIES, MEDICINE, BIOLOGY, NANOTECHNOLOGY, SENSORS, PRACTICAL APPLICATION and INFORMATION. The journal is addressed to researchers, lecturers, university students, engineers. The publisher of the journal is the Nanomaterials Research Institute of "Ivanovo State University".
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