Sertraline induced Stevens-Johnson syndrome - A case series

Stevens-Johnson syndrome is an acute, rare, and potentially fatal skin reactions involving loss of skin and, in some cases, mucosal membranes. Medications are causative in majority of them. Here in the 3 cases, we found sertraline being the causative agent. Majority of the reports on drug induced SJS in our field is related to lamotrigine and only one case report on sertraline causing such manifestation was found in literature. Immunological modifications are proposed reasons behind the same. So, while prescribing comparatively safer agents like sertraline a clinician should carefully monitor such complications.