激光痔疮成形术与Milligan和Morgan痔疮切除术的随机临床试验

حسین شباهنگ, قدرت اله مداح, احمدعلی مفیدی, M. Nooghabi, سعیده حاجبی خانیکی
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引用次数: 8

摘要

简介:痔疮切除术是最常见的外科手术之一,其他治疗方法如激光痔疮切除术已被用作替代方法。本研究的目的是比较激光治疗与开放式痔疮切除术的疗效和术后并发症。材料与方法:将85例二、三度痔疮患者随机分为两组,随访6个月。干预组采用激光痔疮成形术(LHP)治疗,对照组采用Milligan和Morgan痔切除术。随访结束时,80例患者仍在试验中,根据36项简短健康调查问卷(SF-36)研究术后疼痛[视觉模拟量表(VAS)]、并发症和生活质量。数据采用r3.5.1软件分析,p值< 0.05被认为是显著的。结果:最常见的主诉是出血(57%)和疼痛(41%)。两组术后即刻及6个月疼痛差异无统计学意义(p < 0.05)。两组随访均未见并发症。SF-36问卷除一般健康外,其余8个量表在两组间均有显著差异。LHP患者的身体功能较低,而激光组患者在其他量表上的生活质量较好。激光组SF-36总分为66.1±3.6分,手术组为56.0±3.3分(p < 0.001)。结论:激光痔疮切除术是一种安全的手术,术后并发症少。它提高了患者的生活质量,可以替代其他手术方法。
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A Randomized Clinical Trial of Laser Hemorrhoidoplasty vs Milligan and Morgan Hemorrhoidectomy
Introduction: Hemorrhoidectomy is one of the most common surgical procedures, and other treatments such as laser hemorrhoidectomy had been used as an alternative. The aim of this study was to determine the outcome and postoperation complications of treatment by laser compared with open hemorrhoidectomy. Materials and methods: In this randomized clinical trial (RCT), 85 cases with a second or third degree of hemorrhoids were assigned to two groups at random and followed for 6 months. Those patients in the intervention group were treated by laser hemorrhoidoplasty (LHP) and those in the control group underwent Milligan and Morgan hemorrhoidectomy. At the end of follow-up, 80 cases remained in the trial on whom postoperative pain [visual analog scale (VAS)], complications, and quality of life according to the 36-item Short Form Health Survey (SF-36) questionnaire were studied. Data were analyzed using R 3.5.1 software and p value < 0.05 was considered significant. Results: The most common complaints were bleeding (57%) and pain (41%). Postoperative pain immediately and after 6 months was not significantly different between the two groups ( p > 0.05). No complications were seen in any groups in follow-up. All eight scales of SF-36 questionnaire, except general health, were significantly different in the two groups. Physical functioning was lower in patients who underwent LHP, whereas the patients’ quality of life in other scales was better in the laser group. The total score of SF-36 was 66.1 ± 3.6 and 56.0 ± 3.3 in laser and surgery groups, respectively ( p < 0.001). Conclusion: Laser hemorrhoidectomy is a safe procedure, not associated with any excessive postoperative complications. It improves patients’ quality of life and can be a substitution of other surgical methods.
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