胎龄15-30周胎膜早破后新生儿存活率

Rujira Manorompattarasan, Y. Kunpalin, S. Chaithongwongwatthana
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引用次数: 1

摘要

目的:探讨15 ~ 30周胎龄(GA)早产儿胎膜早破(PPROM)的新生儿生存率及相关因素。材料和方法:本回顾性描述性研究通过回顾2002年1月1日至2013年12月31日朱拉隆功国王纪念医院收治的15-30周胎膜早破孕妇的医疗记录进行。采用Logistic回归分析确定各因素与新生儿存活率之间的关系。结果:本组总妊娠数99例,新生儿存活率为80.8%(95%可信区间71.4 ~ 87.8%)。妊娠15 ~ 19+6周PPROM患者的新生儿存活率为16.7%,而妊娠20 ~ 23+6周和24 ~ 30周PPROM患者的新生儿存活率分别为50.0%和92.2%。logistic回归分析显示,与新生儿存活率增加相关的因素包括胎膜早破≥24周时的GA和使用抗早产药物。结论:妊娠中期PPROM的新生儿存活率取决于胎膜早破开始时的GA。胎膜早破≥24周的新生儿比胎膜早破小于24周的新生儿有更多的生存机会。使用溶胎术可提高新生儿存活率。
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Neonatal Survival Rate following Premature Rupture of Membranes at Gestational Age 15-30 Weeks
Objectives: To determine neonatal survival rate and associated factors in pregnancies with preterm premature rupture of membranes (PPROM) at gestational age (GA) between 15 and 30 weeks. Materials and Methods: This retrospective descriptive study was conducted by reviewing the medical records of the pregnant women with premature rupture of membranes (PROM) at 15-30 weeks’ gestation admitted at King Chulalongkorn Memorial Hospital between 1st January 2002 and 31st December 2013. Logistic regression analysis was used to determine association between factors and neonatal survival. Results: The total number of pregnancies in this study was 99 and neonatal survival rate was 80.8% (95% confidence interval 71.4-87.8%). Women with PPROM at GA between 15 and 19+6 weeks had neonatal survival rate of 16.7% while neonatal survival rates of cases with PPROM at 20-23+6 weeks and 24-30 weeks were 50.0% and 92.2%, respectively. Factors associated with increased neonatal survival from logistic regression analysis included GA at PROM ≥ 24 weeks and tocolytic administration. Conclusion: Neonatal survival in pregnancies with midtrimester PPROM depended on GA when PROM started. Neonates in women with PPROM at ≥ 24 weeks’ gestation had more chances to survive than those with PROM at GA less than 24 weeks. Use of tocolysis was associated with increase neonatal survival.
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来源期刊
Thai Journal of Obstetrics and Gynaecology
Thai Journal of Obstetrics and Gynaecology Medicine-Obstetrics and Gynecology
CiteScore
0.40
自引率
0.00%
发文量
3
审稿时长
24 weeks
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