{"title":"转移性雌激素受体阳性子宫平滑肌肉瘤患者对他莫昔芬和节拍环磷酰胺的持久反应","authors":"Tsung-Teh Wu, Hsiang- Hu, T. Chen","doi":"10.4103/JCRP.JCRP_23_20","DOIUrl":null,"url":null,"abstract":"Uterine leiomyosarcoma is a rare uterine malignancy, but the most common type of uterine sarcoma, in which a considerable proportion of tumors express estrogen/progesterone hormone receptors. We report a case of estrogen receptor-positive uterine leiomyosarcoma with a durable response to a combination of tamoxifen and metronomic cyclophosphamide. The current landscape and potential systemic treatment for uterine leiomyosarcoma were also briefly reviewed.","PeriodicalId":31219,"journal":{"name":"Journal of Cancer Research and Practice","volume":"7 1","pages":"174 - 178"},"PeriodicalIF":0.0000,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Durable response to tamoxifen and metronomic cyclophosphamide in a patient with metastatic estrogen receptor-positive uterine leiomyosarcoma\",\"authors\":\"Tsung-Teh Wu, Hsiang- Hu, T. Chen\",\"doi\":\"10.4103/JCRP.JCRP_23_20\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Uterine leiomyosarcoma is a rare uterine malignancy, but the most common type of uterine sarcoma, in which a considerable proportion of tumors express estrogen/progesterone hormone receptors. We report a case of estrogen receptor-positive uterine leiomyosarcoma with a durable response to a combination of tamoxifen and metronomic cyclophosphamide. The current landscape and potential systemic treatment for uterine leiomyosarcoma were also briefly reviewed.\",\"PeriodicalId\":31219,\"journal\":{\"name\":\"Journal of Cancer Research and Practice\",\"volume\":\"7 1\",\"pages\":\"174 - 178\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cancer Research and Practice\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/JCRP.JCRP_23_20\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cancer Research and Practice","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/JCRP.JCRP_23_20","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Durable response to tamoxifen and metronomic cyclophosphamide in a patient with metastatic estrogen receptor-positive uterine leiomyosarcoma
Uterine leiomyosarcoma is a rare uterine malignancy, but the most common type of uterine sarcoma, in which a considerable proportion of tumors express estrogen/progesterone hormone receptors. We report a case of estrogen receptor-positive uterine leiomyosarcoma with a durable response to a combination of tamoxifen and metronomic cyclophosphamide. The current landscape and potential systemic treatment for uterine leiomyosarcoma were also briefly reviewed.
期刊介绍：
JCRP aims to provide an exchange forum for the cancer researchers and practitioners to publish their timely findings in oncologic disciplines. The scope of the Journal covers basic, translational and clinical research, Cancer Biology, Cancer Immunotherapy, Hemato-oncology, Digestive cancer, Urinary tumor, Germ cell tumor, Breast cancer, Lung cancer, Head and Neck Cancer in a vast range of cancer related topics. The Journal also seeks to enhance and advance the cancer care standards in order to provide cancer patients the best care during the treatments.
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