伊拉克库尔德斯坦地区埃尔比勒300例新冠肺炎患者临床及血液学特征分析

Rundk Ahmad Hwaiz, Sahar Mohammed Zaki Abdullah, S. J. Jalal Balaky, K. Ali, M. Merza, Shakhawan Assad Khailani, N. Shabila
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引用次数: 2

摘要

背景COVID-19主要表现为呼吸道感染,但研究表明,它可以被认为是一种全身性疾病,可传播到影响多器官系统,包括呼吸系统、心血管系统、胃肠道、造血系统、神经系统和免疫系统。目的描述和分析库尔德斯坦埃尔比勒地区300例新冠肺炎住院患者的临床和血液学特征。方法回顾性研究纳入2020年9月至2021年2月期间因COVID-19确诊入院的300例任意年龄患者。病例通过鼻咽拭子标本逆转录酶聚合酶链反应诊断。结果21 ~ 40岁患者占比最高。患者最常见的症状为肌痛(66.7%)、疲劳(62.3%)、头痛(50.7%)和胸痛(52.7%)。死亡患者与康复患者血液学和生化指标存在差异。只有康复患者的中期绝对计数百分比(MID%)显著高于死亡患者(6.41% vs. 4.48, p = 0.019)。老年患者(40岁以下)的死亡率明显高于年轻患者(≤40岁)(6.8%比1.3%,p = 0.015),糖尿病患者比非糖尿病患者(10.8%比3%,p = 0.047),有慢性疾病的患者比无慢性疾病的患者(10.6%比2.1%,p = 0.006)。结论新冠肺炎患者血液学和生化指标存在差异。低MID%、年龄较大、存在糖尿病和慢性疾病与COVID-19患者的死亡显著相关。
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Clinical and hematological characteristics of 300 COVID-19 patients in Erbil, Kurdistan Region, Iraq
Background COVID-19 primarily presents as a respiratory tract infection, but studies indicate that it could be considered a systemic disease that can spread to affect multiple organ systems, including respiratory, cardiovascular, gastrointestinal, hematopoietic, neurological, and immune systems. Objective To describe and analyze the clinical and hematological characteristics of 300 hospitalized COVID-19 patients in Erbil, Kurdistan. Methods This retrospective study included 300 patients of any age admitted to hospital due to confirmed COVID-19 between September 2020 and February 2021. Cases were diagnosed by reverse transcriptase polymerase chain reaction assays of nasopharyngeal swab specimens. Results The highest proportion of patients were aged 21–40 years. The most common symptoms among the patients were myalgia (66.7%), fatigue (62.3%), headache (50.7%), and chest pain (52.7%). Differences in hematological and biochemical parameters were observed between deceased and recovered patients. Only the mid-range absolute count percentage (MID%) was significantly higher in the recovered patients than in the deceased ones (6.41% vs. 4.48, p = 0.019). Death was significantly higher among older patients (>40 years) than younger ones (≤40 years) (6.8% vs. 1.3%, p = 0.015), diabetic than non-diabetic (10.8% vs. 3%, p = 0.047), and those having chronic diseases than those without chronic diseases (10.6% vs. 2.1%, p = 0.006). Conclusions Different hematological and biochemical parameter findings were observed among the COVID-19 patients. Low MID%, older age, and presence of diabetes mellitus and chronic disease were significantly associated with death among COVID-19 patients.
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来源期刊
CiteScore
4.00
自引率
0.00%
发文量
88
审稿时长
15 weeks
期刊介绍: International Journal of Immunopathology and Pharmacology is an Open Access peer-reviewed journal publishing original papers describing research in the fields of immunology, pathology and pharmacology. The intention is that the journal should reflect both the experimental and clinical aspects of immunology as well as advances in the understanding of the pathology and pharmacology of the immune system.
期刊最新文献
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