肉毒杆菌毒素注射治疗睡眠磨牙症

Q4 Medicine Sleep Medicine Research Pub Date : 2018-12-30 DOI:10.17241/SMR.2018.00199

Seurin Kim, Keun jeong Park, Y. Shim, S. Kim

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引用次数: 1

摘要

肉毒毒素（BoNT）是一种可逆阻断突触前乙酰胆碱释放的强效神经毒素，已成功应用于治疗严重睡眠磨牙症（SB）。然而，关于BoNT的有效性及其注射方案（如药物剂量和咀嚼肌注射部位）的研究很少。因此，我们回顾了近年来BoNT在SB患者中的应用研究。睡眠医学研究2018；9（2）：73-76

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Botulinum Toxin Injection for Managing Sleep Bruxism

Botulinum toxin (BoNT), a potent neurotoxin that reversibly blocks presynaptic acetylcholine release, has been applied successfully to treat severe sleep bruxism (SB). However, little work has been reviewed on the effectiveness of BoNT and its injection protocol such as drug dose and injection sites in masticatory muscles. Therefore, we reviewed recent studies on application of BoNT in SB patients. Sleep Med Res 2018;9(2):73-76

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