难腹腔镜胆囊切除术的术中预测因素:AMU评分系统

M. S. Akhtar, P. Alam, Y. Alvi, Isna Khan, Syed AA Rizvi, M. Raza
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摘要

导论:即使在困难的胆囊切除术中,腹腔镜也成为外科医生的首选,因此对腹腔镜胆囊切除术(LC)术中困难进行客观分级的需求越来越受欢迎。本研究旨在设计一个评分系统来预测术中LC的困难结果。材料与方法:本研究在某三级医院普外科进行,对象为行LC的患者。持续时间超过70分钟和/或转为开放的手术被认为是困难的LC。为了建立预测评分,通过多元logistic回归分析确定各种因素与胆囊切除术困难的相关性,并绘制受试者工作特征(ROC)曲线来估计评分系统的截止值。结果:我们在这项研究中招募了200例患者,其中85例进行了困难的胆囊切除术。在所有术中预测因素中,粘连、胆囊(GB)状况、卡洛三角状态和异常以及胆囊周围积液的存在与LC困难相关。基于优势比,设计了一个新的评分系统,得分范围从0到25。根据术中因素将评分分为易(0 ~ 5分)和难(6分及以上)。截止评分为6分时,该评分系统的敏感性和特异性分别为87.1和88.7%。结论:本研究表明术中评分系统可以预测LC的困难结局。这有助于减少并发症和转向开腹胆囊切除术,特别是对资金有限的国家,如印度。
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Intraoperative Predictors of Difficult Laparoscopic Cholecystectomy: AMU Scoring System
bstrAct Introduction: With laparoscopy being the surgeon’s first choice even in difficult cholecystectomy, a need to objectively grade intraoperative difficulty during laparoscopic cholecystectomy (LC) is gaining popularity. The study was done to design a scoring system to predict the difficult outcome during intraoperative LC. Materials and methods: The study was done at the General Surgery Department in a tertiary level hospital among patients undergoing LC. The procedures that exceeded 70 minutes in duration and/or converted to open were considered the difficult LC. To develop the predictive score, an association of various factors with difficult cholecystectomy was identified by performing multiple logistic regression analysis, and receiver operating characteristic (ROC) curve was plotted to estimate the cutoff value for the scoring system. Results: We recruited 200 patients in this study, out of which 85 had difficult cholecystectomy procedures. Among all intraoperative predictors, adhesions, gallbladder (GB) condition, Calot’s triangle status and abnormality, and the presence of pericholecystic fluid were associated with a difficult LC. Based on the odds ratio, a new scoring system was designed with a score ranging from 0 to 25. The grading score was created as easy (0 – 5) and difficult (6 or above) based on the intraoperative factors. At a cutoff score of 6, this scoring system had a sensitivity and specificity of 87.1 and 88.7 % , respectively. Conclusion: This study demonstrates that an intraoperative scoring system can predict the difficult outcome of LC. This can help in minimizing the complication and conversion to open cholecystectomy, especially relevant for funds-limited settings like India.
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