颈前路椎间盘切除术治疗单、双层颈椎间盘突出症的疗效评价

H. Mohammed, M. Khalaf, Mohamed Farrah
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All these patients were evaluated preoperatively clinically and radiologically (plain X-rays of cervical spine; A-P, Lateral and dynamic films: flexion, extension and oblique and MRI cervical spine). Nerve conduction study was done to exclude peripheral compression neuropathy and to confirm radiculopathy in selected cases where double entrapment phenomena suspected and followed up for a period of 1 month to 12 months. \nThe technique followed anterior decompression differed according to the way of reconstruction at each level and the patients were accordingly classified into three groups: group A (1-level fusion); where the anterior decompression was accomplished by single level cervical discectomy, and then insertion of cervical cage at this leve, group B (2-level fusion); where the anterior decompression was accomplished by double level cervical discectomy, and then insertion of cervical cage at both levels, group C (hybrid construct); where the anterior decompression was in the form of one level cervical discectomy, followed by cage implantation at this level and another level cervical discectomy followed by insertion of cervical disc prosthesis at the same time. Functional outcome was assessed according to Odom’s criteria. Postoperative plain X-rays of cervical spine (A-P and Lateral) were done at follow-up visits (immediate postoperative, 3 months, 6 months 12 month postoperatively. MRI or CT of the cervical spine is done for patients routinely and for patients not improving or with persistent preoperative complaint or any new neurologic deficit. \nResults and Discussion: The ages in our patient population ranged from 30 to 50 years, with a mean of 40 ± 5.9 years (mean ± standard deviation). 11/20 patients (55%) were males, and 9/20 (45%) were females. The commonest level affected is C5-C6 level. The most common complaint of patients is neck pain and radiculopathy. Anterior cervical discectomy followed by single level cervical fusion was done on 13 patients, while 5 patients were subjected to anterior cervical discectomy followed by double level cervical fusion and another 2 patients had anterior cervical discectomy followed by cervical artificial disc replacement at one level and zero profile implant insertion and fusion at another level. \nRegarding the mean duration of hospital stay it was 2.4 days in the single level group while it was 3.8 days in the double level group and 4 days in the hybrid group. Regarding the functional outcome 9 patients (69.2%) had excellent outcome in the single level group versus 3 patients (60%) In the double level group and 2 patients (100%) in the hybrid group, while there were 3 patients (23.1%) who had good outcome in the single level group and 1 patient (20%) in the double level group, finally only one patient in the single level group and 1 patient in the double level group who had satisfactory outcome. There were 2 complications in this study, one (7.7%) in the single level group and one (20%) in the double level group. In the single level group 1 patient had removal of prosthesis due to device failure and hypermobility. In the double level group, one patient had temporary dysphagia and dysphonia. \nConclusion: Ideal treatment for cervical degenerative disc disease must deal with and improve its three components (axial neck pain, radiculopathy, and myelopathy), normalize cervical spine biomechanics so not to act as a nidus accelerating the degenerative process, and improves the functional outcome of the patient without serious complications. CDR and ACDF are both effective treatment strategies for managing degenerative conditions of the cervical spine. 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引用次数: 1

摘要

简介:颈椎间盘突出和颈椎退行性疾病是颈髓和神经根功能障碍最常见的原因。颈椎神经根病的手术治疗仍存在争议。现在有三种可能的治疗方法,而不是两种可能:不植入任何结构的颈前路椎间盘切除术,融合的颈前路椎间盘切除术,以及椎间盘假体植入的颈前路椎间盘切除术。患者与方法:对20例保守治疗无效的颈椎间盘突出伴神经根病患者行前路减压加颈椎间盘置换术治疗。所有患者术前均进行了临床和影像学评估(颈椎x线平片;A-P,侧位片和动态片:屈曲、伸展、斜位和颈椎MRI)。选择怀疑有双重夹持现象的病例,行神经传导研究排除周围压迫性神经病变,确认神经根病变,随访1 ~ 12个月。根据各节段的重建方式,采用不同的前路减压技术,将患者分为三组:A组(1节段融合);其中前路减压通过单节段颈椎椎间盘切除术完成,然后在该节段插入颈椎笼,B组(2节段融合);其中前路减压通过双节段颈椎椎间盘切除术完成,然后在两节段插入颈椎笼,C组(混合结构);其中前路减压的形式是一节段颈椎间盘切除术,然后在这一节段进行cage植入术,同时在另一节段颈椎间盘切除术后置入颈椎间盘假体。功能结果根据奥多姆的标准进行评估。术后随访时(术后即刻、术后3个月、术后6个月、术后12个月)行颈椎x线平片(A-P和侧位)。颈椎的MRI或CT检查是常规的,对于术前没有改善或持续抱怨或任何新的神经功能缺损的患者。结果与讨论:患者年龄在30 ~ 50岁之间,平均40±5.9岁(平均值±标准差)。男性占11/20(55%),女性占9/20(45%)。受影响最常见的级别是C5-C6级别。患者最常见的主诉是颈部疼痛和神经根病。13例患者行前路椎间盘切除术后单节段颈椎融合术,5例行前路椎间盘切除术后双节段颈椎融合术,2例行前路椎间盘切除术后一节段颈椎人工椎间盘置换术,另一节段行零侧位植入融合术。单级组平均住院时间为2.4天,双级组为3.8天,混合组为4天。在功能结局方面,单水平组为优9例(69.2%),双水平组为优3例(60%),混合组为优2例(100%),单水平组为良3例(23.1%),双水平组为优1例(20%),最后单水平组为优1例,双水平组为优1例(20%)。本研究共发生2例并发症,单水平组1例(7.7%),双水平组1例(20%)。在单节段组中,有1例患者因器械失效和活动过度而切除假体。在双水平组中,有1例患者出现暂时性吞咽困难和发音困难。结论:颈椎退行性椎间盘疾病的理想治疗必须处理和改善其三个组成部分(轴颈痛、神经根病和脊髓病),使颈椎生物力学正常化,使其不成为加速退行性过程的病灶,改善患者的功能结局,无严重并发症。CDR和ACDF都是治疗颈椎退行性疾病的有效治疗策略。没有足够的证据表明哪种技术是最有效的,并提供最持久的症状缓解。
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Evaluation of Different Modalities of Anterior Cervical Discectomy for Treatment of Single and Double Level Cervical Disc Herniation
Introduction: Cervical disc herniation and degenerative disease of the cervical spine are the most common causes of cervical cord and nerve root dysfunction. The surgical treatment of cervical radiculopathy is still controversial. Instead of two possibilities, nowadays three possible treatments concur with each other: anterior cervical discectomy without implantation of any structure, anterior cervical discectomy with fusion, and finally, cervical discectomy with implantation of disc prosthesis. Patients and methods: Twenty patients with cervical disc herniation with radiculopathy, which had not responded to conservative treatment were treated by anterior decompression and cervical disc replacement. All these patients were evaluated preoperatively clinically and radiologically (plain X-rays of cervical spine; A-P, Lateral and dynamic films: flexion, extension and oblique and MRI cervical spine). Nerve conduction study was done to exclude peripheral compression neuropathy and to confirm radiculopathy in selected cases where double entrapment phenomena suspected and followed up for a period of 1 month to 12 months. The technique followed anterior decompression differed according to the way of reconstruction at each level and the patients were accordingly classified into three groups: group A (1-level fusion); where the anterior decompression was accomplished by single level cervical discectomy, and then insertion of cervical cage at this leve, group B (2-level fusion); where the anterior decompression was accomplished by double level cervical discectomy, and then insertion of cervical cage at both levels, group C (hybrid construct); where the anterior decompression was in the form of one level cervical discectomy, followed by cage implantation at this level and another level cervical discectomy followed by insertion of cervical disc prosthesis at the same time. Functional outcome was assessed according to Odom’s criteria. Postoperative plain X-rays of cervical spine (A-P and Lateral) were done at follow-up visits (immediate postoperative, 3 months, 6 months 12 month postoperatively. MRI or CT of the cervical spine is done for patients routinely and for patients not improving or with persistent preoperative complaint or any new neurologic deficit. Results and Discussion: The ages in our patient population ranged from 30 to 50 years, with a mean of 40 ± 5.9 years (mean ± standard deviation). 11/20 patients (55%) were males, and 9/20 (45%) were females. The commonest level affected is C5-C6 level. The most common complaint of patients is neck pain and radiculopathy. Anterior cervical discectomy followed by single level cervical fusion was done on 13 patients, while 5 patients were subjected to anterior cervical discectomy followed by double level cervical fusion and another 2 patients had anterior cervical discectomy followed by cervical artificial disc replacement at one level and zero profile implant insertion and fusion at another level. Regarding the mean duration of hospital stay it was 2.4 days in the single level group while it was 3.8 days in the double level group and 4 days in the hybrid group. Regarding the functional outcome 9 patients (69.2%) had excellent outcome in the single level group versus 3 patients (60%) In the double level group and 2 patients (100%) in the hybrid group, while there were 3 patients (23.1%) who had good outcome in the single level group and 1 patient (20%) in the double level group, finally only one patient in the single level group and 1 patient in the double level group who had satisfactory outcome. There were 2 complications in this study, one (7.7%) in the single level group and one (20%) in the double level group. In the single level group 1 patient had removal of prosthesis due to device failure and hypermobility. In the double level group, one patient had temporary dysphagia and dysphonia. Conclusion: Ideal treatment for cervical degenerative disc disease must deal with and improve its three components (axial neck pain, radiculopathy, and myelopathy), normalize cervical spine biomechanics so not to act as a nidus accelerating the degenerative process, and improves the functional outcome of the patient without serious complications. CDR and ACDF are both effective treatment strategies for managing degenerative conditions of the cervical spine. There is insufficient evidence to show which technique is the most effective and provides the longest-lasting symptom relief.
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