日本DCD捐献者器官移植现状

Q4 Medicine Transplantation Reports Pub Date : 2023-06-01 DOI:10.1016/j.tpr.2023.100131
Kenji Yuzawa
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引用次数: 1

摘要

由于在欧美发达移植国家,DCD供体下的器官捐献已达到平台期,因此DCD供体后的器官捐献已得到积极推广。这导致在心脏骤停后引入体外膜氧合(ECMO),并在患者无法恢复时退出生命支持,从而使心脏骤停后的多个器官切除和移植成为可能。在日本,这些努力并没有得到实施,只有自发性心脏骤停后的DCD捐赠者的肾脏被移植。再加上修改《器官移植法》,允许在脑死亡情况下,在家属同意的情况下进行器官捐献,这大大减少了DCD捐献者的数量。在日本,正在努力引进ECMO,并使患者脱离生命维持系统,以便在心脏骤停后进行多器官捐赠将成为可能,就像在欧洲和美国一样。
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Present status of organ transplantation from DCD donors in Japan

As organ donation under DBD donors has reached a plateau in developed transplantation countries in Europe and the United States, organ donation after DCD donors has been actively promoted. This has led to the introduction of extracorporeal membrane oxygenation (ECMO) after cardiac arrest and withdrawal from life support when the patient is incapable of recovery, enabling the removal and transplantation of multiple organs after cardiac arrest. In Japan, these efforts have not been implemented, and only kidneys have been transplanted from DCD donors after spontaneous cardiac arrest. In addition, the revision of the Organ Transplant Law to allow organ donation under brain death with only family approval has drastically reduced the number of DCD donors. In Japan, efforts are underway to introduce ECMO and to wean patients off life support systems so that multi-organ donation after cardiac arrest will be possible as in Europe and the United States.

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来源期刊
Transplantation Reports
Transplantation Reports Medicine-Transplantation
CiteScore
0.60
自引率
0.00%
发文量
24
审稿时长
101 days
期刊介绍: To provide to national and regional audiences experiences unique to them or confirming of broader concepts originating in large controlled trials. All aspects of organ, tissue and cell transplantation clinically and experimentally. Transplantation Reports will provide in-depth representation of emerging preclinical, impactful and clinical experiences. -Original basic or clinical science articles that represent initial limited experiences as preliminary reports. -Clinical trials of therapies previously well documented in large trials but now tested in limited, special, ethnic or clinically unique patient populations. -Case studies that confirm prior reports but have occurred in patients displaying unique clinical characteristics such as ethnicities or rarely associated co-morbidities. Transplantation Reports offers these benefits: -Fast and fair peer review -Rapid, article-based publication -Unrivalled visibility and exposure for your research -Immediate, free and permanent access to your paper on Science Direct -Immediately citable using the article DOI
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