印度两所三级医院儿科人群的继发性癫痫

Arun Kumar, Thangaraj Marimuthu, Lakshminarayanan Kannan, Vikash Agarwal, D. Nayak
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摘要

目的:了解两所医疗保健中心住院患者继发性癫痫发作的临床特点,包括急性和远端症状性癫痫发作,并评价住院患者继发性癫痫发作的预后。方法:在印度奥里萨邦和泰米尔纳德邦的两家三级医院进行了为期四年的多中心横断面研究。共有274名年龄在6个月至12岁之间的患者参与了这项研究。结构化的形式被用来记录临床模式和继发性癫痫发作的原因。结果:在奥里萨邦和泰米尔纳德邦医院的参与者中,局灶性癫痫发作占67.5%。全身性癫痫发作占32.4%。在奥里萨邦,癫痫发作的主要原因是疟疾、脑瘫和病毒性脑膜炎,而在泰米尔纳德邦,癫痫发作的主要原因是神经囊虫病、脑瘫和病毒性脑膜炎。结论:由于大多数原因是可以预防的,因此必须在公共卫生层面解决这一问题,提供改善的卫生条件和对继发性癫痫发作及其原因的充分认识。同样重要的是,医生熟悉引起继发性癫痫发作的原发性疾病的早期病例检测和治疗。
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Secondary Seizures in the Pediatric Population in Two Tertiary Hospitals in India
Objective: To evaluate the clinical pattern of secondary seizures which includes acute and remote symptomatic seizures among hospitalized patients in two healthcare centers and to assess the outcomes among hospitalized patients having secondary seizures.Methods: This multicentric cross-sectional study was conducted in two tertiary hospitals in Odisha and Tamil Nadu, India, for a period of four years. A total of 274 patients in the age group between 6 months to 12 years participated in the study. A structured proforma was used to document the clinical pattern and causes of the secondary seizures.Results: Among the participants in Odisha and Tamil Nadu hospitals, focal seizures constituted 67.5%. Generalized seizures were present in 32.4%. The key causes of seizures in Odisha were malaria, cerebral palsy, and viral meningitis, while in Tamil Nadu, the causes were neurocysticercosis, cerebral palsy, and viral meningitis.Conclusion: Since the majority of the causes are preventable, it is important to address the issue at the public health level, by providing improved sanitation and adequate awareness on the secondary seizure and its causes. It is also important that the physicians are well conversant with the early case detection and treatment of primary diseases causing secondary seizures.
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