术中给液对McKeown食管胃切除术患者围手术期预后的影响

IF 7 2区 医学 Q1 ONCOLOGY Chinese Journal of Cancer Research Pub Date : 2019-10-01 DOI:10.21147/j.issn.1000-9604.2019.05.04
Hongliang Wu, Wen Wang, Gefei Zhao, Q. Xue
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引用次数: 0

摘要

目的液体治疗是围手术期管理的关键组成部分之一。然而,术中液体(IOF)给药影响麦基翁食管胃切除术后临床结果的证据仍然有限。本研究调查了IOF对麦基翁食管胃切除术后临床结果的影响。方法对2013年7月至2016年7月期间接受麦基翁食管胃切除术的患者进行鉴定。从我们的电子医疗记录和麻醉记录中回顾性收集每个符合条件的患者的术前、术中和术后变量。测定IOF发生率,并比较其与术后临床结果的关系。结果共有546名患者被纳入分析。IOF的中位速率为8.87 mL/kg/h。我们将患者分为两组:低液量组(LFVG<8.87 mL/kg/h,n=273)和高液量组。在倾向评分匹配之前或之后,LFVG和HFVG的术后临床结果没有发现统计学上的显著差异。结论在接受麦基翁食管胃切除术的患者中,IOF给药对临床结果没有影响。还需要进一步的高质量研究来检查IOF给药对麦基翁食管胃切除术后临床结果的影响。
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Effect of intraoperative fluid administration on perioperative outcomes in patients undergoing McKeown esophagogastrectomy
Objective Fluid therapy is one of the key components of perioperative management. However, evidence of intraoperative fluid (IOF) administration affecting clinical outcomes following McKeown esophagogastrectomy remains limited. This study investigated the impact of IOF on clinical outcomes after McKeown esophagogastrectomy. Methods Patients who underwent McKeown esophagogastrectomy between July 2013 and July 2016 were identified. Preoperative, intraoperative and postoperative variables for each eligible patient were retrospectively collected from our electronic medical records and anesthetic records. IOF rates were determined and their relationships to postoperative clinical outcomes were compared. Results A total of 546 patients were enrolled in the analysis. The median IOF rate was 8.87 mL/kg/h. We divided the patients into two groups: a low fluid volume group (LFVG <8.87 mL/kg/h, n=273) and a high fluid volume group (HFVG ≥8.87 mL/kg/h, n=273). No statistically significant differences in postoperative clinical outcomes were found between LFVG and HFVG either before or after propensity score matching. Conclusions No effect of IOF administration on clinical outcomes in patients undergoing McKeown esophagogastrectomy was identified. Further high-quality studies examining the influence of IOF administration on clinical outcomes following McKeown esophagogastrectomy are still needed.
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来源期刊
自引率
9.80%
发文量
1726
审稿时长
4.5 months
期刊介绍: Chinese Journal of Cancer Research (CJCR; Print ISSN: 1000-9604; Online ISSN:1993-0631) is published by AME Publishing Company in association with Chinese Anti-Cancer Association.It was launched in March 1995 as a quarterly publication and is now published bi-monthly since February 2013. CJCR is published bi-monthly in English, and is an international journal devoted to the life sciences and medical sciences. It publishes peer-reviewed original articles of basic investigations and clinical observations, reviews and brief communications providing a forum for the recent experimental and clinical advances in cancer research. This journal is indexed in Science Citation Index Expanded (SCIE), PubMed/PubMed Central (PMC), Scopus, SciSearch, Chemistry Abstracts (CA), the Excerpta Medica/EMBASE, Chinainfo, CNKI, CSCI, etc.
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