{"title":"重组酵母合成抗癌长春花碱","authors":"Tian Ma, Zixin Deng","doi":"10.1093/lifemeta/loac024","DOIUrl":null,"url":null,"abstract":"\n In a recent study published in Nature, Zhang et al. employed an innovative approach by reprogramming and engineering yeast strain for combined biosynthesis of vindoline and catharanthine, followed by an additional in vitro chemical step for the successful synthesis of the anticancer vinblastine.","PeriodicalId":74074,"journal":{"name":"Life metabolism","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Reprograming yeast for anticancer vinblastine synthesis\",\"authors\":\"Tian Ma, Zixin Deng\",\"doi\":\"10.1093/lifemeta/loac024\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n In a recent study published in Nature, Zhang et al. employed an innovative approach by reprogramming and engineering yeast strain for combined biosynthesis of vindoline and catharanthine, followed by an additional in vitro chemical step for the successful synthesis of the anticancer vinblastine.\",\"PeriodicalId\":74074,\"journal\":{\"name\":\"Life metabolism\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-09-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Life metabolism\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/lifemeta/loac024\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Life metabolism","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/lifemeta/loac024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Reprograming yeast for anticancer vinblastine synthesis
In a recent study published in Nature, Zhang et al. employed an innovative approach by reprogramming and engineering yeast strain for combined biosynthesis of vindoline and catharanthine, followed by an additional in vitro chemical step for the successful synthesis of the anticancer vinblastine.
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