7在首尔三星医疗中心进行植入式左心室辅助器的早期经验

Q2 Medicine Heart Asia Pub Date : 2018-04-01 DOI:10.1136/HEARTASIA-2018-APAHFF.7
Cho Yang-Hyun
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引用次数: 0

摘要

韩国的心脏移植数量一直在稳步增长。然而,等待移植的时间也在增加。6年来,我们一直在植入左心室辅助装置(LVAD)。截至2017年10月,已有15名患者在三星医疗中心植入LVAD(见表1)。有5名桥接候选患者和10名目的地治疗(DT)患者。年龄范围为47至81岁。术前6名患者(40%)接受体外膜肺氧合(ECMO)支持,4名患者接受透析。三名患者需要术后临时右侧VAD支持。没有早(30 天)死亡,但有2例晚期死亡。在研究期间,LVAD不在任何韩国保险体系的承保范围内。目前,LVAD的作用仅限于成为候选人或DT的桥梁。然而,在不久的将来,它可能被用于纯粹的移植桥。摘要7表1在韩国首尔三星医疗中心进行的LVAD病例摘要性别/年龄策略INTERMACS简介LVAD ECMO前的病因当前状态M/75 DT 3 DCMP,s/p AVR老年无生存5.2 M/66年DT 3 ICMP,s/p冠状动脉旁路移植术COPD 4.3无生存期 73年M/73 DT 3 DCMP老年1.9岁后无HTx 年F/62 BTC 3 ICMP,s/p CABG外国人(由于HF晚期而无法返回祖国)是2.4生存期 F/79年DT 3 ICMP老年,CKD 2年无生存期 年M/49 BTC 2 ICMP感染,恶病质是1.9生存期 年F/48 BTC 2 DCMP(化疗诱导)癌症13岁后死亡 月F/77 DT 3 ICMP老年13无生存期 月M/62 BTC 2 ICMP感染,恶病质是11生存期 月M/81 DT 1 DCMP,s/p AVR,CABG老年8例无生存 月M/69 DT 2 ICMP肺炎,恶病质是生存期7 月M/47 BTC 2 DCMP(酒精)药物滥用7年无生存期 月M/69 DT 2 ICMP感染,恶病质是存活6个月 月M/74 DT 3 DCMP老年,CKD 5无生存期 月F/80 DT 2 DCMP老年,CKD 4无生存期 月主动脉瓣置换术。BTC,通往候选人资格的桥梁。冠状动脉搭桥术。CKD,慢性肾脏疾病。DCMP,扩张型心肌病。DT,目的地治疗。F、 女性。HTx,心脏移植。ICMP,缺血性心肌病。M、 男性。s/p,状态发布
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7 Early experience with implantable LVAD at samsung medical centre, seoul
The number of heart transplantation in Korea has been growing steadily. However, the waiting time for transplantation is also increasing. For 6 years, we have been implanting left ventricular assist devices (LVAD). Up to October 2017, 15 patients have had LVAD implanted at Samsung Medical Centre (see table 1). There were 5 bridge-to-candidacy patients and 10 destination therapy (DT) patients. Age range was 47 to 81 years. Six patients (40%) were on extracorporeal membrane oxygenation (ECMO) support and 4 were on dialysis preoperatively. Three patients required post-operative temporary right VAD support. There were no early (30 day) deaths, but 2 late deaths occurred. During the study period, LVAD were not covered by any Korean insurance system. At present, the role of LVAD is limited to bridge-to-candidacy or DT. However, in the near future, it may be utilised for purely bridge-to-transplantation. Abstract 7 Table 1 Brief summary of LVAD cases performed at Samsung medical centre, Seoul, South Korea Sex/age Strategy INTERMACS profile Aetiology Reason for LVAD Pre-ECMO Current status M/75 DT 3 DCMP, s/p AVR Old age No Survival for 5.2 years M/66 DT 3 ICMP, s/p CABG COPD No Survival for 4.3 years M/73 DT 3 DCMP Old age No HTx after 1.9 years F/62 BTC 3 ICMP, s/p CABG Foreigner (unable to return to home country due to advanced HF) Yes Survival for 2.4 years F/79 DT 3 ICMP Old age, CKD No Survival for 2 years M/49 BTC 2 ICMP Infection, cachexia Yes Survival for 1.9 years F/48 BTC 2 DCMP (chemotherapy-induced) Cancer Yes Death after 13 months F/77 DT 3 ICMP Old age No Survival for 13 months M/62 BTC 2 ICMP Infection, cachexia Yes Survival for 11 months M/81 DT 1 DCMP, s/p AVR, CABG Old age No Survival for 8 months M/69 DT 2 ICMP Pneumonia, cachexia Yes Survival for 7 months M/47 BTC 2 DCMP (alcoholic) Substance abuse No Survival for 7 months M/69 DT 2 ICMP Infection, cachexia Yes Survival for 6 months M/74 DT 3 DCMP Old age, CKD No Survival for 5 months F/80 DT 2 DCMP Old age, CKD No Survival for 4 months AVR, aortic valve replacement. BTC, bridge-to-candidacy. CABG, coronary artery bypass grafting. CKD, chronic kidney disease. DCMP, dilated cardiomyopathy. DT, destination therapy. F, female. HTx, heart transplantation. ICMP, ischaemic cardiomyopathy. M, male. s/p, status post
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Heart Asia
Heart Asia Medicine-Cardiology and Cardiovascular Medicine
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