AB028.P-7残余胃容量与体重减轻之间是否存在相关性--1年业绩

IF 0.5 4区 医学 Q4 SURGERY Annals of Laparoscopic and Endoscopic Surgery Pub Date : 2020-11-30 DOI:10.21037/ales-2019-bms-39
S. Dogan, A. Ipor, M. Pehlivan
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Simultaneously, leakage testing is also routinely performed. 20 mmHg CO2 gas was delivered to the resected stomach tissue until the air leaked from the stomach and noted. In addition, the resected gastric tissue was filled with saline until the fluid leaked from the stapler line. The patients were divided into three groups according to the remaining gastric tissue volume: (I) group below <60 cc, (II) group 60≤90 cc, (III) group <90 cc and above. BMI, total weight loss, weight loss percentage (EWL%) variables were calculated at 6 and 12 months after LSG. Results: All patients were included in the database after 1 year of follow-up. Sixty-seven patients (57 F/10 M) with a mean age of 36 years (17–56 years) were included in the study. One patient was excluded because the gastric tissue was perforated while removing from the abdomen and 4 patients did not come to the control. The remaining 62 patients were evaluated. The average total stomach volume of patients was 1,280 cc (660–1,945 cc), residual gastric tissue volume was 68 cc (35–120 cc), the volume of the removed stomach was 1,212 cc (600–1,900 cc) and CO2 gas given to the extracted stomach tissue was 1 liter (20 mmHg) (0.5 to 1.4), respectively. Mean body mass index (BMI) was calculated as 47.30 kg/m preoperatively, 30.10 kg/m BMI at the end of the first year after LSG. In Group 1,% EWL was 69.22% in 6 months and% EWL% 79.77 in 1 year; In group 2, EWL% 62.62 in 6 months, EWL% 75.04 in 1 year; In group 3, EWL was 66.74% in 6 months and EWL 72.12% in 1 year. In general, satisfactory weight loss was seen in groups 1 and 2 within 1 year (EWL% 70). In group 3, it was close to these values but not statistically significant. As shown in this graph, although it is not statistically significant, weight loss increases as RGV decreases. Conclusions: The main findings of this study indicate that RGV significantly increases weight loss following surgery. However, although the volume increase in RGV reduced weight loss numerically, this was not statistically significant. The most important mechanism of LSG is to limit food intake by reducing stomach volume. Therefore, postoperative gastric volume is necessary to obtain optimum postoperative results in terms of weight loss. The volume and pressure measurements of the entire stomach, the remaining portion, and the resected portion showed that the removed part was in fact the widest part of the stomach. The remaining stomach volume is less than 10% of the total stomach volume and shows that the portion extracted from the stomach is larger in this operation. In our study, the remaining stomach volume was found below 10% in all three groups. There is another study emphasizing that volume and pressure can be an important factor in the weight loss mechanism in LSG. In this study, we consider the low number of cases and the short-term results to be a negative, undesirable factor in statistical evaluations. Our study describes the direct relationship between gastric volume and low weight loss after LSG surgery. We describe an easily measurable volumetric model to estimate gastric volume after LSG. We also found a direct correlation between increased gastric volume and postoperative low weight loss. However, this was not statistically significant. In order to confirm these findings in the medium and long term, more patients should be investigated with an advanced randomized, prospective study and multivariate analysis.","PeriodicalId":8024,"journal":{"name":"Annals of Laparoscopic and Endoscopic Surgery","volume":" ","pages":""},"PeriodicalIF":0.5000,"publicationDate":"2020-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"AB028. 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引用次数: 0

摘要

背景:腹腔镜袖状胃切除术(LSG)已成为治疗肥胖的一种流行方法。尽管减肥手术失败的原因尚不清楚,但人们认为可能存在高残留胃容量。目的评价LSG术后切除胃容量和残余胃容量对减肥的影响。方法:单中心回顾性研究,包括12个月的随访。67名LSG患者被纳入研究。从技术上讲,在用腹腔镜夹闭合幽门螺杆菌后,用亚甲蓝盐水管腔内松针注射器注射口胃管,并在完全视野下给予残留的胃。当剩余的胃组织停止扩张时,注意给予的液体量。同时,还定期进行泄漏测试。将20mmHg的CO2气体输送到切除的胃组织,直到空气从胃泄漏并被注意到。此外,用生理盐水填充切除的胃组织,直到液体从缝合线泄漏。根据剩余胃组织体积将患者分为三组:(I)<60毫升以下组,(II)60≤90毫升组,(III)<90毫升及以上组。在LSG后6个月和12个月计算BMI、总体重减轻、体重减轻百分比(EWL%)变量。结果:所有患者在随访1年后均被纳入数据库。67名患者(57 F/10 M),平均年龄36岁(17-56岁),被纳入研究。一名患者被排除在外,因为胃组织在从腹部取出时穿孔,4名患者没有进入对照组。其余62名患者接受了评估。患者的平均胃总体积为1280 cc(660–1945 cc),残余胃组织体积为68 cc(35–120 cc),取出的胃体积为1212 cc(600–1900 cc),给予提取的胃组织的CO2气体分别为1升(20 mmHg)(0.5至1.4)。术前平均体重指数(BMI)为47.30 kg/m,LSG后第一年末为30.10 kg/m。在第1组中,6个月内%EWL为69.22%,1年内%EWL%79.77;第2组6个月EWL为62.62,1年EWL为75.04;第3组6个月EWL为66.74%,1年EWL为72.12%。总的来说,第1组和第2组在1年内体重减轻令人满意(EWL%70)。在第3组中,它接近这些值,但没有统计学意义。如图所示,尽管没有统计学意义,但随着RGV的降低,体重减轻会增加。结论:本研究的主要发现表明RGV显著增加了手术后的体重减轻。然而,尽管RGV的体积增加在数值上减少了体重减轻,但这在统计学上并不显著。LSG最重要的机制是通过减少胃容量来限制食物摄入。因此,术后胃容量对于获得最佳的术后减肥效果是必要的。对整个胃、剩余部分和切除部分的体积和压力测量表明,切除部分实际上是胃最宽的部分。剩余的胃体积小于胃总体积的10%,并且表明在该操作中从胃提取的部分更大。在我们的研究中,三组患者的剩余胃容量均低于10%。还有另一项研究强调,体积和压力可能是LSG减肥机制中的一个重要因素。在这项研究中,我们认为病例数量少和短期结果是统计评估中的一个负面、不可取的因素。我们的研究描述了胃容量与LSG手术后低体重减轻之间的直接关系。我们描述了一种易于测量的体积模型来估计LSG后的胃体积。我们还发现胃容量增加与术后低体重减轻之间存在直接相关性。然而,这在统计上并不显著。为了在中长期内证实这些发现,应通过高级随机、前瞻性研究和多变量分析对更多患者进行调查。
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AB028. PP-7 Is there a correlation between residual gastric volume and weight loss?—1 year results
Background: Laparoscopic sleeve gastrectomy (LSG) has become a popular procedure for the treatment of obesity. Although the causes of failure after bariatric surgery are unknown, it is thought that there may be a high residual gastric volume. Objective is to evaluate the effects of resected gastric volume and residual gastric volumes after LSG on weight loss. Methods: A single-center retrospective study including 12 months follow-up. Sixty-seven patients with LSG were enrolled. Technically, after the closure of the pylori with a laparoscopic clamp, an orogastric tube was injected with methylene-blue saline intraluminal pine-tip syringe and the residual stomach was given in full view. The amount of fluid given was noted when the remaining gastric tissue stopped expansion. Simultaneously, leakage testing is also routinely performed. 20 mmHg CO2 gas was delivered to the resected stomach tissue until the air leaked from the stomach and noted. In addition, the resected gastric tissue was filled with saline until the fluid leaked from the stapler line. The patients were divided into three groups according to the remaining gastric tissue volume: (I) group below <60 cc, (II) group 60≤90 cc, (III) group <90 cc and above. BMI, total weight loss, weight loss percentage (EWL%) variables were calculated at 6 and 12 months after LSG. Results: All patients were included in the database after 1 year of follow-up. Sixty-seven patients (57 F/10 M) with a mean age of 36 years (17–56 years) were included in the study. One patient was excluded because the gastric tissue was perforated while removing from the abdomen and 4 patients did not come to the control. The remaining 62 patients were evaluated. The average total stomach volume of patients was 1,280 cc (660–1,945 cc), residual gastric tissue volume was 68 cc (35–120 cc), the volume of the removed stomach was 1,212 cc (600–1,900 cc) and CO2 gas given to the extracted stomach tissue was 1 liter (20 mmHg) (0.5 to 1.4), respectively. Mean body mass index (BMI) was calculated as 47.30 kg/m preoperatively, 30.10 kg/m BMI at the end of the first year after LSG. In Group 1,% EWL was 69.22% in 6 months and% EWL% 79.77 in 1 year; In group 2, EWL% 62.62 in 6 months, EWL% 75.04 in 1 year; In group 3, EWL was 66.74% in 6 months and EWL 72.12% in 1 year. In general, satisfactory weight loss was seen in groups 1 and 2 within 1 year (EWL% 70). In group 3, it was close to these values but not statistically significant. As shown in this graph, although it is not statistically significant, weight loss increases as RGV decreases. Conclusions: The main findings of this study indicate that RGV significantly increases weight loss following surgery. However, although the volume increase in RGV reduced weight loss numerically, this was not statistically significant. The most important mechanism of LSG is to limit food intake by reducing stomach volume. Therefore, postoperative gastric volume is necessary to obtain optimum postoperative results in terms of weight loss. The volume and pressure measurements of the entire stomach, the remaining portion, and the resected portion showed that the removed part was in fact the widest part of the stomach. The remaining stomach volume is less than 10% of the total stomach volume and shows that the portion extracted from the stomach is larger in this operation. In our study, the remaining stomach volume was found below 10% in all three groups. There is another study emphasizing that volume and pressure can be an important factor in the weight loss mechanism in LSG. In this study, we consider the low number of cases and the short-term results to be a negative, undesirable factor in statistical evaluations. Our study describes the direct relationship between gastric volume and low weight loss after LSG surgery. We describe an easily measurable volumetric model to estimate gastric volume after LSG. We also found a direct correlation between increased gastric volume and postoperative low weight loss. However, this was not statistically significant. In order to confirm these findings in the medium and long term, more patients should be investigated with an advanced randomized, prospective study and multivariate analysis.
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