非转移性原发性癌症择期手术治疗良性结直肠吻合口狭窄的非手术治疗

Ümit Mercan, O. Ersen, C. Yüksel, Ö. Yalkın, Serkan Akbulut, Ekrem Ünal, S. Demirci
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摘要

导语:结直肠手术后,由于吻合口渗漏、吻合口缺血等多种原因,良性吻合口狭窄可能在术后或远期发展。虽然手术治疗在过去通常用于良性吻合口狭窄,但手术已将其位置留给了更微创的方法,如内镜治疗。文献中没有关于良性吻合口狭窄的金标准治疗方法。在本研究中,我们旨在介绍我们在非转移性原发性癌症择期手术患者中治疗良性吻合口狭窄的临床经验。材料和方法:在2013年1月至2018年1月期间接受切除和结肠直肠吻合的156名患者被纳入研究。对22例良性吻合口狭窄患者的病因和治疗方法进行了回顾性比较。结果:在22名患者中,9名患者接受了指扩张或球囊扩张治疗,至少2次,最多5次。四名患者接受了扩张术后支架置入术的治疗。其余9名患者接受了手术治疗。在所有狭窄患者中,已确定其中15人有新辅助治疗史,5人有吻合口瘘,其中16人使用了28mm圆形吻合器。讨论与结论:新辅助治疗史、吻合口瘘的存在和28mm环形吻合器的使用已被检测为良性吻合口狭窄发展的最重要病因。内镜治疗应主要用于治疗良性吻合口狭窄。内窥镜方法可以获得高成功率,并且可以提高患者的生活质量。通过这种方法,将减少手术的需要,并可以预防可能的术后并发症。关键词:直肠肿瘤,狭窄,腹腔镜,吻合口狭窄
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Non-operative Management of Benign Colorectal Anastomotic Stenosis in Patients Undergoing Elective Surgery for Non-Metastatic Primary Rectal Cancer
Introduction: Benign anastomosis stenosis may develop in postoperative or long term period due to many reasons such as anastomosis leakage and anastomosis ischemia after colorectal surgery. While surgical treatment was commonly used in benign anastomosis stenosis in the past, surgery has left its place to more minimally invasive methods such as endoscopic treatments. There is no gold standard treatment method in the management of benign anastomosis strictures in the literature. In this study, we aimed to present our clinical experience in the treatment of benign anastomosis strictures in patients undergoing elective surgery for nonmetastatic primary rectal cancer. Material and Methods: One hundred fifty-six (156) patients who underwent resection and colorectal anastomosis between January 2013 and January 2018 were included in the study. 22 patients developed benign anastomotic stenosis has been determined and etiological factors and treatment modalities applied has been compared retrospectively. Results: In 22 patients, 9 patients were treated with digital or balloon dilatation, at least 2 sessions and up to 5 sessions. Four patients were treated with dilatation followed by stenting. The remaining 9 patients were taken to surgical treatment. Among whole patients with stenosis, it has been determined that 15 of them had neoadjuvant therapy history, 5 had anastomosis leakage and in 16 of them 28 mm circular stapler have been used. Discussion and Conclusion: Neoadjuvant treatment history, the presence of anastomosis leakage and the usage of 28 mm circular stapler have been detected to be the most important etiological factors in development of benign anastomotic stenosis. Endoscopic treatments should be tried primarily to treat benign anastomotic stenosis. High success rates can be achieved with endoscopic methods and patient quality of life can be improved. With this approach, the need for surgery will be reduced and possible postoperative complications can be prevented. Keywords: Rectal Neoplasms, Stenosis, Laparoscopy, Anastomostic stenosis
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