Isolated macrostomia with bilateral facial cleft in a preterm neonate

Facial clefts are a rare presentation with defects of the orofacial region associated with abnormalities in the soft tissues and bones. This condition has a variable presentation, often leading to aesthetic problems and feeding difficulty that affect growth and nutrition. We describe a preterm neonate diagnosed with nonsyndromic Tessier type 7 isolated bilateral facial clefts. The evaluation revealed a macrostomia with soft tissue and skin involvement with normal musculature, maxillae, mandible, and other facial bones. Timely recognition and evaluation of this premature neonate aided in better management of this condition. Long-term follow-up remains essential as plastic surgery-guided cosmetic rehabilitation, feeding, and speech therapy assessment are required for a better quality of life.