Comparison of Antibiogram Results of Two Types of Antibiotic Discs and Validation by E.test Method on Bacteria with High Antibiotic Resistance Patterns

Background and Objective: The increased resistance of microorganisms to common antibiotics is one of the major therapeutic challenges for patients. The present study aimed to compare the antibiogram results of two types of antibiotic discs and validate them by the Epsilometer test (E-test) method on bacteria with high antibiotic resistance patterns. Materials and Methods: This descriptive-analytical study was performed by the census method on 176 patients admitted to different wards of Sina Hospital in Hamadan from March 2016 to March 2019. The patients entered the study with a positive culture result and underwent the antibiogram using two types of discs. Following that, validation was performed by the Etest method in cases with significant differences. Finally, the results were described and analyzed in SPSS software (version 16) at a 95% confidence