亚磷酸铝中毒及胃管爆裂1例报告

Faiz Ahmad, Mohd. Kaleem Khan, A. Mahmood, Jamal Azmat
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引用次数: 0

摘要

背景:根据印度国家犯罪记录局(NCRB)2015年的数据,中毒自杀是自杀死亡的第二常见原因(27.9%)。磷化铝(ALP)是用于自杀的主要农业毒药,因为其可用性没有得到适当的监管。ALP是一种剧毒的固体熏蒸杀虫剂、灭鼠剂和杀虫剂。案情介绍:一名40岁女子被警察带到急诊室。她的四肢冰冷,张力低下,皮肤苍白。患者的生命体征不稳定,脉搏频率为112/分钟,血压为68/54毫米汞柱,呼吸频率为22/分钟,体温为30.1摄氏度,呼吸中有强烈的蒜味。在抽吸胃内容物的过程中,住院医生和辅助临床工作人员观察到气体自燃,产生火焰和白色烟雾,声音像爆炸。胃吸出物和Ryle的试管立即被送往法医部门,在那里进行了硝酸银测试,发现磷化氢气体呈强阳性。讨论:磷化铝在胃中容易与水和盐酸反应,产生磷化氢(PH3)和少量二膦。结论:本病例报告强调急诊医生在处理此类患者时需要高度警惕和充分准备。ALP中毒患者释放磷化氢引起的自燃不仅会影响患者,还会对急诊医生和医务人员的健康造成危害。
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Aluminum Phosphide Poisoning and Blast in Gastric Tube: A Case Report
Background: Suicide by poisoning is the second most common cause of death by suicide (27.9%) as per The National Crime Records Bureau (NCRB) India in 2015. Aluminum phosphide (ALP) is the leading agricultural poison used to commit suicide as where its availability is not properly regulated. ALP is a highly toxic solid fumigant pesticide, rodenticide and insecticide. Case presentation: A 40-year-old woman was brought by the police to the emergency section. Her extremities were cold and hypotonic, and her skin was pale. Patient’s vitals were unstable with pulse rate 112/minute irregularities, blood pressure 68/54 mm of Hg, respiratory rate 22/minute shallow and body temperature 30.1 oC and characteristicly strong garlicky odor on her breath. During the suction of gastric contents, spontaneous ignition of gas with flames and white fumes with sound like a blast was observed by resident doctors and para-clinical staff. Gastric aspirate along with Ryle’s tube were immediately sent to the forensic department where the Silver Nitrate test was performed and it was found strongly positive for phosphine gas. Discussion: Aluminum phosphide readily reacts with water and hydrochloric acid in the stomach to produce phosphine (hydrogen phosphide, PH3) and a small amount of diphosphine. Conclusion: The present case report stresses on the need that the emergency physicians need to be highly alert and adequately prepared while handling such patients. Spontaneous ignition with the release of phosphine from ALP poisoned patients can not only affect the patient, but also pose a health hazard to emergency physicians and medical staff.
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期刊介绍: Asia Pacific Journal of Medical Toxicology (APJMT) aims to expand the knowledge of medical toxicology and tries to provide reliable information in this field for medical and healthcare professionals. APJMT mainly focuses on research related to medical toxicology issues in the Asia Pacific region and publishes articles on clinical and epidemiological aspects of toxicology, poisonings emergency care, addiction, drug interactions and adverse effects. The journal accepts and welcomes high quality papers in the form of original articles and rarely review articles, case reports and scientific letters relevant to medical practice in toxicology.
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