肝移植术后De Novo多种食物过敏1例报告

Gül Şeker, Sinem Kahveci Çelik, Y. Öztürk
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引用次数: 0

摘要

食物过敏被定义为免疫介导的对食物的反应。固体器官移植后的食物过敏最早是在1997年肝脏和肾脏移植后描述的。一名三岁五个月大的男性因进食后嘴唇肿胀入院。由于胆道闭锁,他在十个月大时接受了活体捐赠者的肝脏移植。对他克莫司和霉酚酸酯的治疗进行了监测,他因20个月大时在我科吃鸡蛋后立即出现嘴唇肿胀而被送入急诊科。在该病例中没有观察到相关的呼吸道、皮肤或胃肠道检查结果,该病例之前食用过鸡蛋,没有任何问题。后来,在不同时间吃了蜂蜜和芝麻酱混合物、玉米和蛋黄酱后,他的嘴唇和眼睛出现了肿胀。根据测试,鸡蛋、花生和榛子被排除在患者的饮食之外。该病例接受了两年的饮食治疗,没有出现任何问题。器官捐献者应进行食物过敏筛查,以预测器官接受者在移植后出现新的食物过敏的风险。尽管没有证据表明捐赠者对食物过敏,但应记住,接受实体器官移植的患者可能会出现新的食物过敏,应就此对患者进行随访。
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De Novo Multiple Food Allergy After Liver Transplantation: A Case Report
Food allergy is defined as an immune-mediated response to food. Food allergy after solid organ transplantation was first described in 1997 after liver and kidney transplantation. A three years- five-month-old male was admitted with swelling of the lip after food intake. He had received a liver transplant from a living donor at ten months of age due to biliary atresia. Treatment with tacrolimus and mycophenolate mofetil was monitored, and he was admitted to the emergency department with complaints of swelling of the lip that developed immediately after eating eggs in our department at 20 months of age. No associated respiratory, skin, or gastrointestinal findings were observed in the case, who had previously consumed eggs without problems. Later, after consuming honey and tahini mixture, corn with mayonnaise sauce at different times, swelling developed on his lips and eyes. According to tests, egg, peanut, and hazelnut were excluded from the patient's diet. The case was followed up with diet therapy for two years without any problems. Organ donors should be screened for food allergies to predict the risk of organ recipients for new food allergies after transplantation. Although there is no evidence of food allergies in the donor, it should be kept in mind that new food allergy may develop in patients who have undergone solid organ transplantation, and patients should be followed up in this regard.
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