SD BIOLINE检测丙型肝炎病毒诊断准确性的系统评价和荟萃分析

IF 2 Q3 INFECTIOUS DISEASES Infectious microbes & diseases Pub Date : 2023-03-29 DOI:10.1097/IM9.0000000000000117
Shu-Chang Weng, Jie Zhou, Xiaoni Zhong, Qing Xin, Yue-Xue Mai, Li Ji, Ya-ping Li, Xun-Jie Cao, W. Yang, Hao Chen, Xu-guang Guo
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摘要

摘要丙型肝炎病毒(HCV)是一种在全球广泛传播的核糖核酸病毒,通过血液和性接触传播。在经济欠发达地区,其发病率和死亡率尤其高。因此,迫切需要一种经济有效的丙型肝炎病毒诊断方法。在本研究中,我们评估了SD BIOLINE快速诊断试验对丙型肝炎病毒检测的诊断准确性。我们在PubMed、Embase、Web of Science和Cochrane Library中搜索了与SD BIOLINE和HCV相关的研究,然后设计了纳入和排除标准。在提取有效数据后,使用质量评估工具诊断准确性研究的质量评估对纳入的文献进行评估。在我们的数据分析后,确定了诊断方法的灵敏度、特异性、阳性似然比、阴性似然比、诊断准确度、总结受试者操作特征曲线、漏斗图、箱图和Fagan图。最终收录了九篇文章和九组数据。敏感性和特异性分别为0.94和0.98,阳性似然比为79.53,阴性似然比为0.05,诊断优势比为1590.32,总结受试者工作特性曲线为0.9958。SD BIOLINE试验诊断丙型肝炎具有灵敏度高、特异性强、成本低、操作简便等优点。因此,我们建议使用SD BIOLINE快速有效地筛查丙型肝炎病毒,特别适用于经济欠发达地区。
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Assessing the Diagnostic Accuracy of SD BIOLINE for Detection of Hepatitis C Virus: A Systematic Review and Meta-analysis
Abstract Hepatitis C virus (HCV) is a globally widespread ribonucleic acid virus that transmits through blood and sexual contact. Its morbidity and mortality are particularly higher in economically underdeveloped areas. Therefore, an economical and effective diagnostic method for detection of HCV is urgently needed. In this study, we evaluated the diagnostic accuracy of the SD BIOLINE rapid diagnostic test for HCV detection. We searched for studies related to SD BIOLINE and HCV in PubMed, Embase, Web of Science, and the Cochrane Library and then designed inclusion and exclusion criteria. After extracting valid data, the included literature was evaluated with the quality assessment tool Quality Assessment of Diagnostic Accuracy Studies. After our data analysis, the sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic accuracy, summary receiver operating characteristic curve, funnel plot, box plot, and Fagan plot of the diagnostic method were determined. Nine articles with nine sets of data were finally included. The sensitivity and specificity were 0.94 and 0.98, respectively, the positive likelihood ratio was 79.53, the negative likelihood ratio was 0.05, the diagnostic odds ratio was 1590.32, and the summary receiver operating characteristic curve was 0.9958. The SD BIOLINE test has the advantages of high sensitivity, high specificity, low cost, and easy operation for diagnosing HCV. Therefore, we recommend using SD BIOLINE for rapid and effective screening of HCV, which is especially applicable for economically underdeveloped areas.
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