Selectivity of Tryptophan and Phenylalanine Adsorption by Activated Coconut Carbon of Medical Assignment

The adsorption capacity of carbon adsorbent KARBON™ for tryptophan and phenylalanine from the individual solutions, their mixtures, and in the presence of leucine, isoleucine, and valine has been studied. It is established that, at the adsorption from the mixture of these amino acids, the overall removal of tryptophan and phenylalanine is an order of magnitude exceeding the removal of aliphatic analogues. Maximum removals (>90%) of tryptophan and phenylalanine are achieved at concentrations of 2.0-2.8 mmol/L, as the concentrations increase to 20-24 mmol/L, the efficiency of the removal of these amino acids is decreased approximately twice. The obtained data show that the enterofraction of the adsorbent KARBON™ can be used as an alternative to amino acid therapy for various diseases.