聚类性分析的相似统计量及其在细胞形成问题中的应用

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2018-12-02 DOI:10.1155/2018/1348147
Yingyu Zhu, Simon Li
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引用次数: 0

摘要

本文提出使用相似性值的统计来评估与细胞形成(CF)问题相关的可聚类性或结构性。通常,在CF问题得到解决之前,无法知道CF解决方案的结构性。在这种背景下,本文研究了机器对的相似性统计,以在不求解给定CF问题的情况下估计其潜在的结构性。一个关键的观察结果是,结构良好的CF解矩阵具有相对较高的高相似性机器对百分比。然后,使用直方图作为统计工具来研究相似度值的统计分布。这项研究导致了U形标准和基于Kolmogorov-Smirnov检验的标准的发展。因此,开发了一种程序来分类输入CF问题是否可能导致结构良好或结构不良的CF矩阵。在数值研究中,最初使用20个矩阵来确定标准的阈值,并使用40个额外的矩阵来验证结果。此外,这些矩阵示例表明,遗传算法不能有效地改进通过分层聚类(作为一种启发式方法)获得的结构良好的CF解决方案(具有高分组功效值)。这一结果支持了相似性统计与预先确定输入CF问题实例的相关性,并提出了解决问题的正确方法。
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Similarity Statistics for Clusterability Analysis with the Application of Cell Formation Problem
This paper proposes the use of the statistics of similarity values to evaluate the clusterability or structuredness associated with a cell formation (CF) problem. Typically, the structuredness of a CF solution cannot be known until the CF problem is solved. In this context, this paper investigates the similarity statistics of machine pairs to estimate the potential structuredness of a given CF problem without solving it. One key observation is that a well-structured CF solution matrix has a relatively high percentage of high-similarity machine pairs. Then, histograms are used as a statistical tool to study the statistical distributions of similarity values. This study leads to the development of the U-shape criteria and the criterion based on the Kolmogorov-Smirnov test. Accordingly, a procedure is developed to classify whether an input CF problem can potentially lead to a well-structured or ill-structured CF matrix. In the numerical study, 20 matrices were initially used to determine the threshold values of the criteria, and 40 additional matrices were used to verify the results. Further, these matrix examples show that genetic algorithm cannot effectively improve the well-structured CF solutions (of high grouping efficacy values) that are obtained by hierarchical clustering (as one type of heuristics). This result supports the relevance of similarity statistics to preexamine an input CF problem instance and suggest a proper solution approach for problem solving.
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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