{"title":"心脏磁共振成像中的应变:在描述整体左心室机械功能中的应用","authors":"O. Werner, F. Raimondi","doi":"10.1016/j.acvdsp.2023.07.026","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p><span><span>Nowadays, the fraction of ejection (FE) is no longer considered as the unique way of expression of the efficiency of cardiac labor. The development of strain imaging (SI), in </span>echocardiography and in MRI, has led to a better understanding of </span>ventricular contraction<span>, especially in cases of cardiac dysfunction with preserved FE. But SI still under-exploited in clinical practice despite the fact that it is a proved prognostic factor<span> in many cardiomyopathies. Recently, a new framework was developed to associate the FE and the deformation parameters, the global longitudinal (GLS) and circular strain (GCS), to give the opportunity of a global assessment of the cardiac function. This mathematical relationship was validated on the adult population. This work intends to determine the more accurate evaluation of the GCS and GLS values in pediatric population and its use in order to validate the mathematic model described.</span></span></p></div><div><h3>Methods</h3><p><span>Retrospective monocentric study carried out in the cardiopediatric unit of Florence University Hospital. Inclusion of all pediatric patients who completed cardiac MRI between November 2021 and December 2022. An assessment of the </span>left ventricle FE, GCS and GLS and a double reading was made by two specialized cardiologists.</p></div><div><h3>Results/Expected results</h3><p>In total, 134 CMR were studied. A good reproducibility between readers was observed (GCS: r<!--> <!-->=<!--> <!-->0,94, GLS: r<!--> <!-->=<!--> <!-->0,83). The correlation between isolated strain parameters and FE (GCS: r<!--> <!-->=<!--> <!-->0,84 and GLS: r<!--> <!-->=<!--> <!-->0,68) and between theorical FE (GCS<!--> <!-->+<!--> <!-->GLS) and FE was high (FE/FE(th): r<!--> <!-->=<!--> <span>0,88). The use of endocardial strain and the assessment of GCS with short axis slice assured the best correlation with the FE.</span></p></div><div><h3>Conclusion/Perspectives</h3><p>The evaluation of GCS and GLS with CMR are a safe way to evaluate the mechanical contraction of the left ventricle in pediatric population. The use of an integrated mathematical formula gives a summarized information of SI with a very good correlation to the FE.</p></div>","PeriodicalId":8140,"journal":{"name":"Archives of Cardiovascular Diseases Supplements","volume":null,"pages":null},"PeriodicalIF":18.0000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Strain in cardiac magnetic resonance imaging: Utility in the description of the global mechanical left ventricle function\",\"authors\":\"O. Werner, F. Raimondi\",\"doi\":\"10.1016/j.acvdsp.2023.07.026\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p><span><span>Nowadays, the fraction of ejection (FE) is no longer considered as the unique way of expression of the efficiency of cardiac labor. The development of strain imaging (SI), in </span>echocardiography and in MRI, has led to a better understanding of </span>ventricular contraction<span>, especially in cases of cardiac dysfunction with preserved FE. But SI still under-exploited in clinical practice despite the fact that it is a proved prognostic factor<span> in many cardiomyopathies. Recently, a new framework was developed to associate the FE and the deformation parameters, the global longitudinal (GLS) and circular strain (GCS), to give the opportunity of a global assessment of the cardiac function. This mathematical relationship was validated on the adult population. This work intends to determine the more accurate evaluation of the GCS and GLS values in pediatric population and its use in order to validate the mathematic model described.</span></span></p></div><div><h3>Methods</h3><p><span>Retrospective monocentric study carried out in the cardiopediatric unit of Florence University Hospital. Inclusion of all pediatric patients who completed cardiac MRI between November 2021 and December 2022. An assessment of the </span>left ventricle FE, GCS and GLS and a double reading was made by two specialized cardiologists.</p></div><div><h3>Results/Expected results</h3><p>In total, 134 CMR were studied. A good reproducibility between readers was observed (GCS: r<!--> <!-->=<!--> <!-->0,94, GLS: r<!--> <!-->=<!--> <!-->0,83). The correlation between isolated strain parameters and FE (GCS: r<!--> <!-->=<!--> <!-->0,84 and GLS: r<!--> <!-->=<!--> <!-->0,68) and between theorical FE (GCS<!--> <!-->+<!--> <!-->GLS) and FE was high (FE/FE(th): r<!--> <!-->=<!--> <span>0,88). The use of endocardial strain and the assessment of GCS with short axis slice assured the best correlation with the FE.</span></p></div><div><h3>Conclusion/Perspectives</h3><p>The evaluation of GCS and GLS with CMR are a safe way to evaluate the mechanical contraction of the left ventricle in pediatric population. The use of an integrated mathematical formula gives a summarized information of SI with a very good correlation to the FE.</p></div>\",\"PeriodicalId\":8140,\"journal\":{\"name\":\"Archives of Cardiovascular Diseases Supplements\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":18.0000,\"publicationDate\":\"2023-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of Cardiovascular Diseases Supplements\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1878648023002471\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Cardiovascular Diseases Supplements","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1878648023002471","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
目前,射血分数(FE)已不再被认为是衡量心脏分娩效率的唯一指标。应变成像(SI)的发展,在超声心动图和MRI,导致更好地了解心室收缩,特别是在心脏功能障碍的情况下保留FE。尽管SI是许多心肌病的预后因素,但它在临床实践中仍未得到充分利用。最近,一种新的框架被开发出来,将FE和变形参数,整体纵向(GLS)和圆形应变(GCS)联系起来,为心脏功能的整体评估提供了机会。这种数学关系在成年人群中得到了验证。本工作旨在确定儿童GCS和GLS值的更准确评估及其应用,以验证所描述的数学模型。方法在佛罗伦萨大学医院心脏科进行回顾性单中心研究。纳入2021年11月至2022年12月期间完成心脏MRI的所有儿科患者。由两名专业心脏病专家评估左心室FE、GCS和GLS,并进行双读数。结果/预期结果共研究了134例CMR。读者间重复性好(GCS: r = 0.94, GLS: r = 0.83)。分离应变参数与FE(GCS: r = 0.84, GLS: r = 0.68)、理论FE(GCS + GLS)与FE之间的相关性较高(FE/FE(th): r = 0.88)。心内膜应变和短轴片评估GCS与FE的相关性最好。结论/观点CMR评价GCS和GLS是评价小儿左心室机械收缩的一种安全方法。综合数学公式的使用给出了SI的汇总信息,与FE有很好的相关性。
Strain in cardiac magnetic resonance imaging: Utility in the description of the global mechanical left ventricle function
Introduction
Nowadays, the fraction of ejection (FE) is no longer considered as the unique way of expression of the efficiency of cardiac labor. The development of strain imaging (SI), in echocardiography and in MRI, has led to a better understanding of ventricular contraction, especially in cases of cardiac dysfunction with preserved FE. But SI still under-exploited in clinical practice despite the fact that it is a proved prognostic factor in many cardiomyopathies. Recently, a new framework was developed to associate the FE and the deformation parameters, the global longitudinal (GLS) and circular strain (GCS), to give the opportunity of a global assessment of the cardiac function. This mathematical relationship was validated on the adult population. This work intends to determine the more accurate evaluation of the GCS and GLS values in pediatric population and its use in order to validate the mathematic model described.
Methods
Retrospective monocentric study carried out in the cardiopediatric unit of Florence University Hospital. Inclusion of all pediatric patients who completed cardiac MRI between November 2021 and December 2022. An assessment of the left ventricle FE, GCS and GLS and a double reading was made by two specialized cardiologists.
Results/Expected results
In total, 134 CMR were studied. A good reproducibility between readers was observed (GCS: r = 0,94, GLS: r = 0,83). The correlation between isolated strain parameters and FE (GCS: r = 0,84 and GLS: r = 0,68) and between theorical FE (GCS + GLS) and FE was high (FE/FE(th): r = 0,88). The use of endocardial strain and the assessment of GCS with short axis slice assured the best correlation with the FE.
Conclusion/Perspectives
The evaluation of GCS and GLS with CMR are a safe way to evaluate the mechanical contraction of the left ventricle in pediatric population. The use of an integrated mathematical formula gives a summarized information of SI with a very good correlation to the FE.
期刊介绍:
Archives of Cardiovascular Diseases Supplements is the official journal of the French Society of Cardiology. The journal publishes original peer-reviewed clinical and research articles, epidemiological studies, new methodological clinical approaches, review articles, editorials, and Images in cardiovascular medicine. The topics covered include coronary artery and valve diseases, interventional and pediatric cardiology, cardiovascular surgery, cardiomyopathy and heart failure, arrhythmias and stimulation, cardiovascular imaging, vascular medicine and hypertension, epidemiology and risk factors, and large multicenter studies. Additionally, Archives of Cardiovascular Diseases also publishes abstracts of papers presented at the annual sessions of the Journées Européennes de la Société Française de Cardiologie and the guidelines edited by the French Society of Cardiology.