维生素b和胆碱的补充改变了缺血的大脑

Journal of young investigators Pub Date : 2019-04-01 DOI:10.22186/JYI.36.4.44-49

P. Keerthi, N. Jadavji

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引用次数: 1

摘要

据报道，在大鼠中给予BDNF可以降低肿瘤坏死因子α (TNF-α)的表达，同时增加抗炎细胞因子的水平。这表明BDNF可能通过减少炎症来减轻缺血性损伤(Jiang et al.， 2011)。最后，BDNF可以抑制谷氨酸诱导的神经毒性，通过在树突中积累激活酪氨酸kib -维生素和胆碱的补充改变缺血脑

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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B-Vitamin and Choline Supplementation Changes the Ischemic Brain

Administration of BDNF in rats has also been reported to reduce the expression of tumor necrosis factor alpha (TNF-α), an inflammatory molecule, while increasing levels of anti-inflammatory cytokines. This suggests that BDNF may reduce ischemic damage by reducing inflammation (Jiang et al., 2011). Finally, BDNF can inhibit neurotoxicity induced by glutamate in cultured cortical neurons by accumulating in dendrites to activate the tyrosine kiB-Vitamin and Choline Supplementation Changes the Ischemic Brain

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Journal of young investigators

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