腹骶部切除术与腹会阴部切除术在低位直肠癌患者的暴露/手术时间/出血方面

R. Dutta, Sujitesh Saha, M. Saha, Abhimanyu Basu, Soumen Das, D. Saha
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引用次数: 0

摘要

背景:癌症占所有结直肠癌的近30%,仍然是一个重要的医学和社会问题。腹部切除术(APR)仍然是直肠癌患者的首选手术。APR的另一种选择是腹骶切除术(ASR)。目的:我们旨在评估肿瘤的各种表现模式、人口统计学特征和组织病理学特征,并从暴露、手术时间、出血等方面评估ASR对APR的疗效,尤其是在手术的会阴/骶骨部分。设计:这是一项前瞻性观察性研究。背景:这项研究是在印度东部的一家超专科政府医院进行的。患者和方法:将诊断为低位直肠癌的患者纳入研究。使用抽样理论的分层模型形成两组;一组接受APR,另一组接受ASR。主要疗效指标:对于低位癌症患者,ASR是一种可行的方法,出血减少,剖切的会阴部/骶部手术时间减少,暴露更好,肿瘤结果良好。样本量:30名参与者被纳入研究。结果:在全部研究参与者中,63%为男性,36%为女性。30多岁和40多岁的患者是最常见的受影响年龄组。直肠出血是最常见的表现。最常见的组织学肿瘤是高分化腺癌。ASR的平均手术时间和解剖会阴/骶骨部分的平均失血量小于APR。此外,ASR的暴露量更好。接受ASR的患者中有93%接受了全直肠系膜切除术。结论:ASR是治疗低位直肠癌的可行方法,在某些方面比APR表现更好。局限性:本研究持续时间短,患者数量较少。利益冲突:无。
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Abdominosacral resection versus abdominoperineal resection in patients with low rectal carcinoma in terms of exposure/operating time/bleeding
Background: Comprising nearly 30% of all colorectal cancers, rectal cancer continues to be a significant medical and social problem. Abdominiperineal resection (APR) remains the procedure of choice for patients with rectal carcinoma. An alternative to APR is abdominosacral resection (ASR). Objective: We aim to assess the various modes of presentation, demographic profiles, and histopathological characteristics of tumors, and evaluate the efficacy of ASR over APR in terms of exposure, operating time, bleeding, etc., especially in the perineal/sacral part of the procedure. Design: This was a prospective observational study.Setting: This study was conducted at a superspeciality government hospital in eastern India. Patients and Methods: Patients diagnosed with low rectal carcinoma were included in the study. Two groups were formed using a stratified model of sampling theory; one group underwent APR while the other ASR. Main Outcome Measures: For patients with low rectal cancer, ASR is a feasible approach with reduced bleeding, lesser operating time in the perineal/sacral part of dissection, better exposure, and good oncological outcome.Sample Size: Thirty participants were included in the study. Results: Of the total study participants, 63% were males and 36% females. Patients in their 30s and 40s were the most commonly affected age group. Per-rectal bleeding was the most common presentation. The most common histological tumor encountered was well-differentiated adenocarcinoma. The mean operating time and mean blood loss with regards to the perineal/sacral part of the dissection was less in ASR than that in APR. In addition, the exposure was better in ASR. Ninety-three percent of the patients undergoing ASR had total mesorectal excision. Conclusion: ASR is a feasible approach for low rectal carcinoma and performs better in certain aspects than APR. Limitations: This study had a short duration and included less number of patients. Conflict of Interest: None.
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