A Decline in Aminotransferase Activity Due to Lifestyle Modification in Children with NAFLD

Ad dress for Cor res pon den ce Pawel Malecki MD, Poznan University of Medical Sciences, Department of Infectious Diseases and Child Neurology, Poznan, Poland Phone: +48618491319 E-mail: pmalecki@ump.edu.pl ORCID: orcid.org/0000-0002-0651-4454 Re cei ved: 02.08.2020 Ac cep ted: 28.09.2020 Introduction Non-alcoholic fatty liver disease (NAFLD) is currently the most common chronic liver illness in children (1). This term describes a broad spectrum of liver disorders, ranging from simple steatosis to non-alcoholic steatohepatitis. Its estimated prevalence ranges from 3% to 12% in the general pediatric population and up to 70% in obese children (2). Suspicion of liver steatosis is usually based on imaging studies a characteristic, hyperechogenic picture of the liver in abdominal ultrasound is the most commonly used mode of assessment. Diagnosis is established by excluding other causes of liver damage (drug poisoning, viral hepatitis, autoimmune liver disease, inborn errors of metabolism, alcoholism) (3,4).