弥合皮肤病学和精神病学之间的差距:继发于神经精神药物的刮伤障碍的流行和治疗

Psych Pub Date : 2023-07-05 DOI:10.3390/psych5030043
Brittany M. Thompson, Joshua M. Brady, J. McBride
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引用次数: 0

摘要

(1) 背景:本研究中的皮肤病和拔毛癖是指药物诱导的强迫症(OCDs)的一个子类。患有典型的皮肤炎或拔毛癖的患者通常会出现其他强迫症症状,尽管在当前文献中发现的药物诱导的皮肤脱落或拔毛症病例中并不存在这种症状。本文旨在探讨药物性银屑病的发病率和治疗方法。(2) 方法:在PubMed数据库中查询药物诱导的皮肤炎或拔毛癖病例。数据库搜索得到80个结果,其中7个是英文的完整病例报告,具有可接受的临床过程细节,共产生9名患者。(3) 结果:所有停用不良药物的患者症状均完全缓解。继续服药的患者在接受额外药物治疗时症状得到了缓解。非典型抗精神病药物和SSRIs在某些情况下也被认为是犯罪因素,但在其他情况下是成功的治疗方法。(4) 结论:对于皮肤病或拔毛癖患者,停止使用冒犯性药物或增加额外药物治疗的效果最好。血清素和多巴胺水平异常被认为与这种疾病的病理学有关。
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Bridging the Gap between Dermatology and Psychiatry: Prevalence and Treatment of Excoriation Disorders Secondary to Neuropsychiatric Medications
(1) Background: The dermatillomania and trichotillomania disorders in this study refer to the subcategory of obsessive-compulsive disorders (OCDs) that are medication-induced. Patients with typical dermatillomania or trichotillomania disorder generally present with other OCD symptoms, although this is not present in the cases of medication-induced skin picking or hair pulling disorders found in the current literature. This paper serves to investigate the prevalence and treatment methods of medication-induced excoriation disorders. (2) Methods: The PubMed database was queried for cases of medication-induced dermatillomania or trichotillomania. The database search resulted in 80 results, 7 of which were full-length case reports in English with acceptable detail on clinical course, yielding nine patients. (3) Results: All patients who discontinued their offending agent had complete resolution of symptoms. Patients who continued their medications saw a resolution of symptoms when treated with an additional medication. Atypical antipsychotics and SSRIs were also noted to have been the offending agent in some cases but a successful treatment in other cases. (4) Conclusion: Patients who discontinued their offending agent or added additional pharmacotherapy for dermatillomania or trichotillomania had the best outcomes. Abnormal serotonin and dopamine levels are thought to be connected to the pathology of this disease.
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