波兰卢布林65岁以上人群腹主动脉瘤患病率及危险因素分析

IF 0.4 Q4 PERIPHERAL VASCULAR DISEASE Acta Angiologica Pub Date : 2019-03-20 DOI:10.5603/AA.2019.0001
J. Tkaczyk, S. Przywara, Michał Terpiłowski, Klaudia Brożyna, M. Iłżecki, P. Terlecki, T. Zubilewicz
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引用次数: 3

摘要

腹主动脉瘤(AAA)是一种非常适合筛查的疾病。基于超声的筛查符合世界卫生组织筛查计划的所有标准,并且有大量证据支持其有效性。在现有文献中,与动脉瘤形成相关的危险因素包括高龄、男性、吸烟、高血压、动脉粥样硬化性疾病以及家族或个人主动脉瘤史。该研究的目的是评估波兰卢布林65岁以上人群中腹主动脉瘤的发病率,并确定危险因素与腹主动脉瘤发病率之间的相关性。材料和方法:2018年5月在波兰卢布林对65岁以上的男性和女性进行了一项单中心筛查研究。患者行基础超声筛查,测量腹主动脉和髂动脉直径。结果:1032例患者,年龄65 ~ 91岁,中位年龄71.37岁。其中女性569人,男性463人。检测到27个主动脉瘤,其中7个在女性组,20个在男性组。本研究中AAA总发生率为2.62%;女性1.23%,男性4.32%。男性、吸烟、冠状动脉疾病、心肌梗死史均为AAA发生的主要危险因素,相对危险度为2.75 ~ 4.53。腹主动脉中位直径为19.24 mm,不同危险因素组腹主动脉中位直径不同。结论:在筛查人群中估计的AAA患病率在先前出版物报道的范围内,然而,它可能证实了最近一些研究显示的AAA患病率下降的趋势。本研究证实了AAA与其主要危险因素(男性、吸烟、冠状动脉疾病和心肌梗死史)之间的相关性,以及AAA与高血压之间的弱相关性和与糖尿病的负相关性。
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Prevalence and risk factors of abdominal aortic aneurysm among over 65 years old population in Lublin, Poland
Introduction: Abdominal aortic aneurysm (AAA) is a disease exceptionally well suited to screening. Ultrasound- based screening meets all criteria for a screening program according to the WHO, and there is a large evidence supporting its usefulness. Risk factors, mentioned in the available literature, associated with aneurysm formation are advanced age, male gender, tobacco smoking, hypertension, atherosclerotic disease and family or personal history of aortic aneurysms. The aim of the study was to evaluate the incidence of abdominal aortic aneurysms in the population of men and women older than 65 years, in Lublin, Poland and to identify the correlation between risk factors and the AAA incidence. Material and methods: A single-center screening study, for men and women older than 65-years was conducted in Lublin, Poland in May 2018. Patients underwent basic screening ultrasound with measurement of the diameter of abdominal aorta and iliac arteries. Each patient completed anonymous questionnaire to investigate risk factors of developing AAA. Results: 1032 patients, aged 65–91 (median age 71.37) were examined. 569 of them were women and 463 men. 27 aortic aneurysms were detected — 7 in a group of women and 20 in a group of men. The total incidence rate of AAA in our study was 2.62%; 1,23% in women and 4,32% in men. Male gender, cigarette smoking, coronary artery disease and a history of myocardial infarction all appeared to be major risk factors of AAA, with relative risk ranging from 2,75 to 4.53. The median diameter of the abdominal aorta was 19.24 mm and varied in groups of patients with different risk factors. Conclusions: The estimated prevalence of AAA in the screened population is within the range of the values reported in previous publications, however, it may confirm a trend of declining prevalence of AAA showed in some recent studies. The presented study confirms the correlation between the AAA and its major risk factors (male sex, smoking cigarettes, coronary artery disease and history of myocardial infarct) as well as a weak association between AAA and hypertension and a negative correlation with diabetes.
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来源期刊
Acta Angiologica
Acta Angiologica PERIPHERAL VASCULAR DISEASE-
CiteScore
0.30
自引率
0.00%
发文量
16
审稿时长
26 weeks
期刊介绍: Acta Angiologica is a bilingual (Polish/English) quarterly for angiologists and vascular surgeons as well as for other doctors interested in vascular disorders. Original papers, reviews, case reports and letters submitted by authors from different countries, concerning physiology, pathology, presentation, diagnostics and treatment of vascular system, are published. Thorough contents of Acta Angiologica provide valuable information about modern diagnostic and therapeutic issues as well as advances in basic sciences and pharmacology.
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