麻醉师在器官捐献中的作用

Q4 Medicine Transplantation Reports Pub Date : 2022-12-01 DOI:10.1016/j.tpr.2022.100116
Julius Balogh , Srikar Jonna , Geraldine Diaz , George W Williams , Marina Moguilevitch , Evan G Pivalizza
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引用次数: 1

摘要

随着可移植器官的持续短缺,对脑死亡和心脏死亡供体的最佳护理对于优化珍贵器官的质量和数量至关重要。麻醉师是围手术期手术回收过程的关键部分,尽管他们个人很少关心供体。尽管存在指导麻醉师处理伦理或临床问题的教育资源,以及重症监护病房和器官采购组织的协议作为维持器官功能的有用模板,但为具体临床实践提供信息的前瞻性数据很少。术前复苏,优化和体内平衡策略应继续进入手术室。为了钝化交感神经和脊髓反射,可能需要谨慎滴入低剂量的麻醉和镇痛药物,但不应加重低血压,建议放松肌肉以方便手术暴露。麻醉师应该了解捐赠过程的程序和药物方面,包括在确认死亡后,当计划取肺时,对已故捐赠者进行重新插管。
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The role of anesthesiologists in organ donation

With the continued deficit of available organs for transplantation, optimal care of the brain-dead and cardiac death donor is essential to optimize quality and quantity of precious organs. Anesthesiologists are a critical part of the perioperative surgical retrieval process, although individually, may rarely care for a donor. Prospective data to inform specific clinical practices is sparse although educational resources exist to guide anesthesiologists with ethical or clinical questions and protocols from intensive care units and organ procurement organizations serve as useful templates for maintenance of organ function. Pre-surgical resuscitation, optimization and homeostatic strategies should be continued into the operating room. Cautious titration of low dose anesthetic and analgesic agents may be required to blunt sympathetic and spinal reflexes but should not aggravate hypotension and muscle relaxation is recommended to facilitate surgical exposure. Anesthesiologists should be aware of procedural and pharmaceutical aspects of the donation process, including re-intubation of a deceased donor after death is confirmed when lung retrieval is planned.

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来源期刊
Transplantation Reports
Transplantation Reports Medicine-Transplantation
CiteScore
0.60
自引率
0.00%
发文量
24
审稿时长
101 days
期刊介绍: To provide to national and regional audiences experiences unique to them or confirming of broader concepts originating in large controlled trials. All aspects of organ, tissue and cell transplantation clinically and experimentally. Transplantation Reports will provide in-depth representation of emerging preclinical, impactful and clinical experiences. -Original basic or clinical science articles that represent initial limited experiences as preliminary reports. -Clinical trials of therapies previously well documented in large trials but now tested in limited, special, ethnic or clinically unique patient populations. -Case studies that confirm prior reports but have occurred in patients displaying unique clinical characteristics such as ethnicities or rarely associated co-morbidities. Transplantation Reports offers these benefits: -Fast and fair peer review -Rapid, article-based publication -Unrivalled visibility and exposure for your research -Immediate, free and permanent access to your paper on Science Direct -Immediately citable using the article DOI
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