{"title":"环糊精基分子在超分子复合物形成中的宿主作用及其实际应用综述","authors":"R. Periasamy","doi":"10.1080/07328303.2021.1967970","DOIUrl":null,"url":null,"abstract":"<div><p>The excellent biocompatibility and unique inclusion capability as well as powerful functionalization capacity of cyclodextrins and their derivatives make them especially attractive for engineering novel functional materials for many applications. There has been increasing interest recently to fabricate supramolecular systems based on cyclodextrin materials. This review focuses on state-of-the-art and recent advances in the construction of cyclodextrin-based assemblies and their practical applications in many fields like gene therapy, chemotherapy, antimicrobial drug delivery, metal extraction, food industry, etc. Supramolecular self-assembly materials based on cyclodextrins are also discussed in this review. The fabrication technologies of supramolecular systems including nanoplatforms and hydrogels as well as their applications in nanomedicine and pharmaceutical sciences are highlighted. In the end, the future directions of this field are discussed.</p><p><span><figure><span><img><ol><li><span>Download : <span>Download high-res image (942KB)</span></span></li><li><span>Download : <span>Download full-size image</span></span></li></ol></span></figure></span></p></div>","PeriodicalId":15311,"journal":{"name":"Journal of Carbohydrate Chemistry","volume":"40 4","pages":"Pages 135-155"},"PeriodicalIF":1.2000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":"{\"title\":\"Cyclodextrin-based molecules as hosts in the formation of supramolecular complexes and their practical applications—A review\",\"authors\":\"R. Periasamy\",\"doi\":\"10.1080/07328303.2021.1967970\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The excellent biocompatibility and unique inclusion capability as well as powerful functionalization capacity of cyclodextrins and their derivatives make them especially attractive for engineering novel functional materials for many applications. There has been increasing interest recently to fabricate supramolecular systems based on cyclodextrin materials. This review focuses on state-of-the-art and recent advances in the construction of cyclodextrin-based assemblies and their practical applications in many fields like gene therapy, chemotherapy, antimicrobial drug delivery, metal extraction, food industry, etc. Supramolecular self-assembly materials based on cyclodextrins are also discussed in this review. The fabrication technologies of supramolecular systems including nanoplatforms and hydrogels as well as their applications in nanomedicine and pharmaceutical sciences are highlighted. In the end, the future directions of this field are discussed.</p><p><span><figure><span><img><ol><li><span>Download : <span>Download high-res image (942KB)</span></span></li><li><span>Download : <span>Download full-size image</span></span></li></ol></span></figure></span></p></div>\",\"PeriodicalId\":15311,\"journal\":{\"name\":\"Journal of Carbohydrate Chemistry\",\"volume\":\"40 4\",\"pages\":\"Pages 135-155\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Carbohydrate Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/org/science/article/pii/S0732830322000040\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Carbohydrate Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S0732830322000040","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Cyclodextrin-based molecules as hosts in the formation of supramolecular complexes and their practical applications—A review
The excellent biocompatibility and unique inclusion capability as well as powerful functionalization capacity of cyclodextrins and their derivatives make them especially attractive for engineering novel functional materials for many applications. There has been increasing interest recently to fabricate supramolecular systems based on cyclodextrin materials. This review focuses on state-of-the-art and recent advances in the construction of cyclodextrin-based assemblies and their practical applications in many fields like gene therapy, chemotherapy, antimicrobial drug delivery, metal extraction, food industry, etc. Supramolecular self-assembly materials based on cyclodextrins are also discussed in this review. The fabrication technologies of supramolecular systems including nanoplatforms and hydrogels as well as their applications in nanomedicine and pharmaceutical sciences are highlighted. In the end, the future directions of this field are discussed.
期刊介绍:
The Journal of Carbohydrate Chemistry serves as an international forum for research advances involving the chemistry and biology of carbohydrates. The following aspects are considered to fall within the scope of this journal:
-novel synthetic methods involving carbohydrates, oligosaccharides, and glycoconjugates-
the use of chemical methods to address aspects of glycobiology-
spectroscopic and crystallographic structure studies of carbohydrates-
computational and molecular modeling studies-
physicochemical studies involving carbohydrates and the chemistry and biochemistry of carbohydrate polymers.