环糊精基分子在超分子复合物形成中的宿主作用及其实际应用综述

IF 1.2 4区 化学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of Carbohydrate Chemistry Pub Date : 2021-01-01 DOI:10.1080/07328303.2021.1967970
R. Periasamy
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引用次数: 6

摘要

环糊精及其衍生物具有良好的生物相容性、独特的包合性和强大的功能化能力,使其成为具有广泛应用前景的工程新型功能材料。近年来,基于环糊精材料制备超分子体系的研究日益引起人们的兴趣。本文综述了环糊精基复合物的构建及其在基因治疗、化疗、抗菌药物传递、金属提取、食品工业等领域的实际应用。本文还对基于环糊精的超分子自组装材料进行了综述。重点介绍了纳米平台和水凝胶等超分子体系的制备技术及其在纳米医学和制药科学中的应用。最后,对该领域的发展方向进行了展望。下载:下载高清图片(942KB)下载:下载全尺寸图片
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Cyclodextrin-based molecules as hosts in the formation of supramolecular complexes and their practical applications—A review

The excellent biocompatibility and unique inclusion capability as well as powerful functionalization capacity of cyclodextrins and their derivatives make them especially attractive for engineering novel functional materials for many applications. There has been increasing interest recently to fabricate supramolecular systems based on cyclodextrin materials. This review focuses on state-of-the-art and recent advances in the construction of cyclodextrin-based assemblies and their practical applications in many fields like gene therapy, chemotherapy, antimicrobial drug delivery, metal extraction, food industry, etc. Supramolecular self-assembly materials based on cyclodextrins are also discussed in this review. The fabrication technologies of supramolecular systems including nanoplatforms and hydrogels as well as their applications in nanomedicine and pharmaceutical sciences are highlighted. In the end, the future directions of this field are discussed.

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来源期刊
Journal of Carbohydrate Chemistry
Journal of Carbohydrate Chemistry 化学-生化与分子生物学
CiteScore
2.10
自引率
0.00%
发文量
20
审稿时长
1 months
期刊介绍: The Journal of Carbohydrate Chemistry serves as an international forum for research advances involving the chemistry and biology of carbohydrates. The following aspects are considered to fall within the scope of this journal: -novel synthetic methods involving carbohydrates, oligosaccharides, and glycoconjugates- the use of chemical methods to address aspects of glycobiology- spectroscopic and crystallographic structure studies of carbohydrates- computational and molecular modeling studies- physicochemical studies involving carbohydrates and the chemistry and biochemistry of carbohydrate polymers.
期刊最新文献
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