生活方式训练对血脂异常儿童和青少年血脂的影响:一项准实验研究

Electronic Physician Pub Date : 2018-11-25 DOI:10.19082/7348
A. Yaghoobi, F. Taheri, Marjan Farzad, T. Kazemi
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引用次数: 0

摘要

背景:血脂异常是心血管疾病最重要的危险因素之一。它会导致成年后这些疾病的发病率上升。生活方式的改变是心血管疾病发生率、预后和并发症的决定因素。目的:本研究旨在评估生活方式改变对患有血脂异常的儿童和青少年血脂的影响。方法:本准实验研究(设计前后)于2015年在伊朗Birjand医学科学大学心血管疾病研究中心对所有患有血脂异常的儿童和青少年进行。参与者接受了6次适合其年龄的训练,包括脂肪定义和健康生活方式。在研究之前和训练后6个月,在相同的情况下,对受试者进行血脂和血压水平检查。使用配对样本t检验、Pearson相关系数和独立样本t检验对数据进行分析。P值小于0.05被认为具有统计学意义。结果:本研究对50例血脂异常儿童进行了研究,其中52%为女性,48%为男性。参与者的平均年龄为12.77±1.84岁。研究显示,胆固醇的平均值之间存在显著差异(p0.05)。Pearson相关系数显示,生活方式改变导致的儿童这些变量的平均值与其年龄之间没有显著关系(p>0.05),营养和充足的睡眠和休息可以作为一种非药物补充剂有效地降低血脂和血脂异常。作为治疗计划的一部分,在诊断出血脂异常后,生活方式改变培训对儿童及其父母都至关重要。
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Impact of lifestyle training on serum lipids of children and adolescents with dyslipidemia: a quasi-experimental study
Background: Dyslipidemia is one of the most important risk factors for cardiovascular diseases. It can cause a rise in the incidence of these diseases in adulthood. Lifestyle modification is a determinant factor for incidence, prognosis and complications of cardiovascular diseases. Objective: The aim of the study was to evaluate the effect of lifestyle modification on serum lipids of children and adolescents with dyslipidemia. Methods: This quasi-experimental study (before and after design) was conducted on all dyslipidemia children and adolescents with dyslipidemia referred to the cardiovascular diseases research center of Birjand University of Medical Sciences (Iran) in 2015. Participants underwent 6 sessions of training, appropriate to their age, including fat definition and healthy lifestyle. Before the study and 6 months after trainings, in the same circumstances, subjects were examined for level of blood lipids and blood pressure. Data were analyzed using paired-samples ttest, Pearson correlation coefficient, and independent-samples t-test. P-value of less than 0.05 was considered statistically significant. Results: This study was performed on 50 children with dyslipidemia, of whom 52% were female and 48% were male. The mean age of participants was 12.77±1.84 years. The study showed a significant difference between the mean of cholesterol (p<0.001) and LDL (p=0.008) before and after the study. Comparing the changes made in the mean of variables such as FBS, Cholesterol, TG, HDL and LDL as a result of gender-based lifestyle modification, no significant difference between the two sexes was seen (p>0.05). Pearson correlation coefficient showed no significant relationship between the mean of these variables in children as a result of lifestyle modification and their age (p>0.05). Conclusion: Lifestyle modification relying on exercise and physical activity, nutrition and sufficient sleep and rest can be effective as a non-pharmacological supplement in reducing blood lipids and dyslipidemia. Lifestyle modification training is essential for both children and their parents after diagnosis of dyslipidemia as a part of the Therapeutic plan.
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