Phytochemical Evaluation of Extracts and Pharmacological Activity of Polyherbal Emulgel

Ocimum sanctum, Rubia cordifolia, Glycyrrhiza glabra, and Punica granatum are all used to treat various diseases and conditions in Ayurvedic medicine. In this study, we aimed to formulate and evaluate a polyherbal emulgel containing extracts from four different medicinal plants: O. sanctum, R. cordifolia, G. glabra, and P. granatum. Different gel formulations were created by combining a base component with extracts from O. sanctum, R. cordifolia, G. glabra, and P. granatum. pH, viscosity, rheology, appearance, and homogeneity were some of the criteria examined for each formulation. They were tested for evaporation and irritation of the epidermis with patches. The cup plate method was used to examine the antibacterial-antifungal activity of formulations against Escherichia coli, Pseudomonas aeruginosa, and Aspergillus niger. Results showed that the inhibition zones produced by all formulations were greater than those produced by the control. Antimicrobial characteristics can be found in polyherbal gels. Synergy between the plant components in the blend produced the desirable outcome.