吲哚菁绿色给药可能导致肝病患者外周氧饱和度升高——一项未被重视的观察

IF 0.2 Q4 ANESTHESIOLOGY Journal of Neuroanaesthesiology and Critical Care Pub Date : 2022-09-01 DOI:10.1055/s-0042-1760270

Mukilan Balasubramanian, Ankita Dey, Rajasekar Ramadurai, A. Kuberan

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引用次数: 1

摘要

显微镜集成吲哚青绿视频血管造影术（ICG-VA）用于评估动脉瘤手术期间夹闭和脑血管流动的完整性。1它是一种比术中数字减影血管造影术（DSA）更实用、耗时更少的替代方案。ICG可引起外周血氧饱和度（SpO2）下降。2-4我们报告了一名48岁的男性，他主诉颅内悸动性头痛1个月，没有任何癫痫发作或局灶性神经疾病史。该患者在过去20年中是一名已知的酒鬼。肝功能检查显示高胆红素血症，血清转氨酶升高。大脑非集中性计算机断层扫描显示蛛网膜下腔出血。DSA扫描发现，患者大脑前循环中有两个动脉瘤，一个在前交通动脉，另一个在右侧M1大脑中动脉。他被安排进行开颅手术并夹闭两个动脉瘤。ICG（Aurogeren、Aurolab、Madurai、Tamil Nadu、India），剂量为0.25mg/kg

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Indocyanine Green Administration May Cause an Exaggerated Peripheral Oxygen Desaturation in the Presence of Liver Disease—An Underemphasized Observation

Microscope-integrated indocyanine green video angiography (ICG-VA) is used to assess the completeness of clipping and cerebral vascular ﬂ ow during aneurysm surgery. 1 It is a more practical and less time-consuming alternative to intraoperative digital subtraction angiography (DSA). ICG has been reported to cause a decrease in peripheral oxygen saturation (SpO 2 ). 2 – 4 We report a 48-year-old male who presented with complaints of holocranial throbbing headache for 1 month without any history of seizures or focal neurological de ﬁ cit. The patient was a known alcoholic for the past 20 years. Liver function test showed hyperbilirubinemia and elevat-ed serum transaminases. Noncontrast computed tomogra-phy brain revealed subarachnoid hemorrhage. The patient was found to have two aneurysms in the anterior cerebral circulation, one in the anterior communicating artery and one in the right M1 middle cerebral artery, on a DSA scan. He was scheduled for a craniotomy and clipping of both aneurysms. ICG (Aurogreen, Aurolab, Madurai, Tamil Nadu, India) at a dose of 0.25mg/kg

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