胃食管反流病(GERD)患病率的述评

Katie H. A. Boulton, P. Dettmar
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引用次数: 11

摘要

近年来,胃食管反流病(GERD)已成为世界范围内的一种常见病,影响着大多数国家和人群。消化系统的历史可以追溯到14世纪,并报道了胃是如何处于酸性环境的。后来发现,在某些情况下,胃的酸性和内容物反流到食道会对人的健康造成有害影响。最早的反流病报告开始于1935年,被描述为消化性食道。许多胃反流患者抱怨胃反流,这是胃内容物从胃回流到食道、喉咙、肺和气道。据目前所知,胃食管反流有多种症状,如反刍、咳嗽和胃灼热,极大地影响了个人的生活质量(QOL)。随着人们对胃食管反流病病理认识的提高,许多治疗方法和药物得以开发、临床评估和在世界范围内使用。为了深入了解胃食管反流在全球的流行程度,本综述将报告其在世界不同国家和地区的流行情况,并报告与胃食管反流相关的相关原因。年龄、肥胖、怀孕、压力、吸烟和饮酒对反流的影响将与饮食的作用以及某些食物和饮料如何引发反流事件一起进行审查。未来对胃反流患病率的研究将有助于教育人们选择生活方式来控制胃反流症状,从而提高生活质量,预防胃反流和与胃反流相关的疾病。GERD中的GERD
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A narrative review of the prevalence of gastroesophageal reflux disease (GERD)
: Over the years gastroesophageal reflux disease (GERD) has become a common disease worldwide affecting most countries and their populations. The history of the digestive system dates back to the 1400’s and reports on how the stomach had an acidic environment. The acidity and contents of the stomach refluxing up into the esophagus was later found in some cases to cause detrimental effects to one’s health. The earliest reports of reflux disease began in 1935 and was described as peptic esophagus. Many GERD patients complain of reflux, which is a back flow of gastric contents from the stomach into the esophagus, throat, lungs and airways. It is knowledge in the present day that GERD has a variety of symptoms such as regurgitation, coughing and heartburn greatly impacting on an individual’s quality of life (QOL). An increased awareness of the pathology of GERD has allowed for a number of treatments and medicines to be developed, clinically evaluated and used worldwide. To gain an insight into how prevalent GERD is globally, this review will aim to report on its prevalence in different countries and regions of the world and report on the relevant causes associated with GERD. The influence of age, obesity, pregnancy, stress, smoking and alcohol on GERD will be reviewed along with the role of diet and how certain foods and drinks can trigger reflux events. Future research of the prevalence of GERD will help to educate people on lifestyle choices to manage GERD symptoms which in turn will improve quality of life and prevent GERD and GERD related diseases. GERD in GERD
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