姜科砂仁根中黄酮类化合物的研究

Deden Indra Dinata, R. Maharani, Fauzan Muttaqien, U. Supratman, M. N. Azmi, Y. Shiono
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引用次数: 0

摘要

砂仁是姜科植物之一,是印度尼西亚西爪哇岛的特有植物。本研究旨在测定A.compactum Sol正己烷提取物中黄酮类化合物的化学结构。前马顿根。根的干燥粉末用正己烷、乙酸乙酯和甲醇溶剂连续提取。从A.compactum Sol根中分离得到三种黄酮类化合物,即5-羟基-3,7,4'-三甲氧基山奈酚(1)、5-羟基-37,3'、4'-四甲氧基山奈酚(2)和4'-羟基-3,5,7-三甲氧基山奈酚(3)。前Maton。化合物1-3的化学结构通过包括红外1D-NMR、2D-NMR和HRTOF-MS的光谱数据以及通过与先前报道的光谱数据的比较来鉴定。化合物1-3是首次从该植物中分离得到,并显示出清除DPPH自由基的活性。
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Flavonoids from the Roots of Amomum compactum Soland Ex Maton (Zingiberaceae)
Amomum compactum Soland Ex Maton is one of the Zingiberaceae family plants which is the endemic plants from West Java, Indonesia. This study was aimed to determine the chemical structure of flavonoid compounds from n-hexane extract of A.compactum Sol. Ex Maton roots. Dried powder of the roots was extracted consecutively with n-hexane, ethyl acetate, and methanol solvents. Three flavonoids, 5-hydroxy-3,7,4`-trimethoxy kaempferol (1), 5-hydroxy-3,7,3',4'-tetra methoxy kaempferol (2) and 4'-hydroxy-3,5,7-trimethoxy kaempferol (3), have been isolated from the roots of A. compactum Sol. Ex Maton.  The chemical structures of compounds 1-3 were identified by spectroscopy data including infrared 1D-NMR, 2D-NMR and HRTOF-MS as well as by comparison with previously reported spectral data. Compounds 1-3 were isolated from this plant for the first time and showed free radical DPPH scavenging activity.
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
15
审稿时长
24 weeks
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