Erb‐（IL10）2通过激活和募集淋巴结CD8+T细胞诱导放射治疗的脓肿抗肿瘤作用

Q4 Medicine Precision Radiation Oncology Pub Date : 2021-05-12 DOI:10.1002/pro6.1138

Y. Yao, Z. Qi, Qingqing Zhu, Qi Zhao, Zheng Zhang, S. Fu, Liyao Zhou, Jiaxing Zhu, Zhenhua Liu, Haiyan Xu, Yuhui Huang, J. Xue, S. Qin

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引用次数: 0

摘要

尽管放射治疗(RT)已广泛应用于癌症治疗，但由于其罕见的体外抗肿瘤作用，它对转移性癌症患者的益处有限。肿瘤免疫治疗的最新进展为提高放射治疗的体外抗肿瘤作用提供了一种潜在的新策略。

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Erb‐(IL10)2 induces abscopal antitumor effects of radiotherapy through the activation and recruitment of lymph node CD8+ T cells

Although radiotherapy (RT) has been widely used in cancer treatment, it provides limited benefits in patients with metastatic cancers due to rare abscopal antitumor effects. Recent progress in cancer immunotherapy provides a potential new strategy to boost the abscopal antitumor effects of RT.

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