带状疱疹:一种病态的临床实体

S. Swain, R. Paul
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引用次数: 4

摘要

水痘带状疱疹病毒(VZV)在面神经膝状神经节处的再活化产生带状疱疹病毒。带状疱疹(HZO)患者通常表现为耳蜗前庭功能障碍,耳痛,耳廓和外耳道水疱疹。HZO患者通常表现为听力丧失、眩晕和面神经麻痹。当它与面神经麻痹相关联时,被称为拉姆齐·亨特综合征(RHS)。在大多数情况下,眩晕患者有听力损失,而没有听力损失的患者没有眩晕。它是一种自限性病毒性疾病,常因面神经麻痹而发病。如果HZO没有得到及时诊断和治疗,通常会发展为RHS。临床医生教育对于早期发现HZO/RHS至关重要,这样可以预防面神经麻痹以及相关的发病率。在这篇综述文章中,我们讨论了目前的概念和最近的进展,在病因,诊断和治疗HZO。
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Herpes Zoster Oticus: A Morbid Clinical Entity
The reactivation of varicella zoster virus (VZV) at the geniculate ganglion of the facial nerve results in herpes zoster virus. Patients of herpes zoster oticus (HZO) often present with symptoms related to the cochleovestibular dysfunction along with otalgia and vesicular eruption at the pinna and external auditory canal. Patients of HZO usually present with hearing loss, vertigo, and facial nerve paralysis. When it is associated with facial nerve paralysis, HZO is called Ramsay Hunt syndrome (RHS). In the majority of cases, patients with vertigo have hearing loss, whereas patients without hearing loss have no vertigo. It is a self-limiting viral disease and the morbidity is often caused due to facial nerve paralysis. If HZO is not diagnosed immediately and treated timely often it progress to RHS. Clinician education is vital for detecting the HZO/RHS at an early stage so that facial nerve paralysis can be prevented along with associated morbidity. In this review article, we discuss the current concept and recent advances in the etiopathology, diagnosis, and treatment of HZO.
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