Siriraj医院重度子痫前期妇女早发性重度子痫前期患病率、危险因素和妊娠结局

Rattiya Phianpiset, B. Phattanachindakun, D. Boriboonhirunsarn
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引用次数: 2

摘要

目的:确定Siriraj医院重度先兆子痫妇女中早发性重度先兆子痫的患病率、相关因素和结果。材料和方法:共有220名被诊断为重度先兆子痫的孕妇被纳入研究。从医疗记录中检索相关数据,包括产科数据、诊断、治疗、分娩途径、孕产妇和新生儿结局。估计了早发性重度先兆子痫(在妊娠34周前诊断)的患病率。比较早发组和晚发组的各种特征,以确定相关的风险因素。结果:孕妇平均年龄28.6岁,未产妇占59.1%。第一次产前检查时的平均胎龄为14.5周,分娩时的平均孕龄为36.2周。早发性重度子痫前期的患病率为15.9%。只有9.1%接受了预期治疗,32.7%通过阴道分娩。平均出生体重为2514.1克。死产、小于胎龄(SGA)、出生窒息和新生儿重症监护室(NICU)入院的比例分别为1.8%、17.7%、2.7%和6.8%。早发组分娩时平均GA为30.6周,晚发组为37.2周。早发组比晚发组更有可能接受预期治疗(34.3%对4.3%;p<0.001)。早发组新生儿更常见更糟糕的结局,他们更可能需要新生儿重症监护室入院(37.1%对1.1%,p<0.001。(35.7%对13.2%,p=0.037)。结论:在Siriraj医院的先兆子痫妇女中,早发性重度先兆子痫的患病率为15.9%。在早发性病例中,更常见的是更糟糕的新生儿结局。先兆子痫是唯一可能的重要相关因素。
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Prevalence, Risk Factors, and Pregnancy Outcomes of Early-onset Severe Preeclampsia among Severe Preeclamptic Women in Siriraj Hospital
Objectives: To determine the prevalence, associated factors and outcomes of early-onset severe preeclampsia among severe preeclamptic women in Siriraj Hospital. Materials and Methods: A total of 220 pregnant women diagnosed with severe preeclampsia were enrolled. Relevant data including obstetric data, diagnosis, treatment, route of delivery, maternal and neonatal outcomes were retrieved from medical records. Prevalence of early-onset severe preeclampsia (diagnosed before 34 weeks of gestation) was estimated. Various characteristics were compared between early and late-onset groups to determine associated risk factors. Results: Mean age of pregnant women was 28.6 years, and 59.1% were nulliparous. Mean gestational age (GA) at first antenatal visit was 14.5 weeks and mean GA at delivery was 36.2 weeks. Prevalence of early-onset severe preeclampsia was 15.9%. Only 9.1% received expectant management and 32.7% delivered vaginally. Mean birth weight was 2514.1 g. Stillbirth, small for gestational age (SGA), birth asphyxia and neonatal intensive care unit (NICU) admission was found in 1.8%, 17.7%, 2.7%, and 6.8%, respectively. Mean GA at delivery was 30.6 weeks in early-onset group and 37.2 weeks among late-onset group. Early-onset group was more likely to receive expectant management than late-onset group (34.3% vs. 4.3%; p<0.001). Worse outcomes were more common among neonates of early-onset group and they were significantly more likely to require NICU admission (37.1% vs. 1.1%, p<0.001). Women with previous preeclampsia were significantly more likely to develop early-onset severe preeclampsia. (35.7% vs. 13.2%, p=0.037). Conclusion: Prevalence of early-onset severe preeclampsia among preeclamptic women in Siriraj hospital was 15.9%. Worse neonatal outcomes were more commonly observed among early-onset cases. Previous preeclampsia was the only significant possible associated factors.
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来源期刊
Thai Journal of Obstetrics and Gynaecology
Thai Journal of Obstetrics and Gynaecology Medicine-Obstetrics and Gynecology
CiteScore
0.40
自引率
0.00%
发文量
3
审稿时长
24 weeks
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