抗严重急性呼吸系统综合征冠状病毒2型候选药物的现状

Q4 Biochemistry, Genetics and Molecular Biology 解放军医学杂志 Pub Date : 2021-06-01 DOI:10.11855/j.issn.0577-7402.2021.06.16
D. Luo, Yongqiang Deng, C. Qin
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引用次数: 1

摘要

截至2021年4月19日,由严重急性呼吸系统综合征冠状病毒2型(SARS-CoV-2)引起的2019冠状病毒病已在全球200多个国家或地区感染了一亿四千万人,并导致三亿六千多人死亡。目前还没有针对新冠肺炎感染患者的特效药,但随着对SARS-CoV-2病毒学特征和发病机制的进一步了解,已经确定了一些潜在的药物靶点。一些候选药物在临床前或临床试验中显示出对严重急性呼吸系统综合征冠状病毒2型的良好抗病毒活性。本文综述了新冠肺炎潜在治疗药物的现状,为今后新冠肺炎的治疗提供参考。DOI:10.11855/j.issn.577-7402.2021.06.16
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Current status of drug candidates against SARS-CoV-2
By April 19, 2021, the ongoing coronavirus disease 2019 (COVID-2019), which is caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) has infected more than one hundred and fourty million individuals across more than 200 countries or territories and killed more than three million twenty-six thousand individuals worldwide. There are currently no specific drugs available for patients with COVID-19 infection, but a number of potential drug targets have been identified with the further understanding of the virological characteristics and pathogenesis of SARS-CoV-2. Some candidate drugs have shown good antiviral activity against SARS-CoV-2 in preclinical or clinical trials. This paper summarizes the current status of potential therapeutic drugs for COVID-19 in order to provide references for future COVID-19 therapy. DOI: 10.11855/j.issn.0577-7402.2021.06.16
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解放军医学杂志
解放军医学杂志 Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)
CiteScore
1.00
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0.00%
发文量
14732
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期刊最新文献
Current status of drug candidates against SARS-CoV-2 Recent advances in vaccine development of severe acute respiratory syndrome coronavirus 2 Analyses of the clinical features of 13 corona virus disease 2019 non-survivors Current status of clinical trial registration regarding coronavirus disease 2019 The interpretation of Consensus on emergency surgery and infection prevention and control for severe trauma patients with 2019 novel corona virus pneumonia
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