鼻内窥镜切除非血管纤维瘤鼻窦及眶尖血管瘤的体会

H. Başak, C. Meço
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摘要

背景:鼻内镜下鼻内窥镜治疗鼻腔炎症和肿瘤已被广泛接受并使用多年。本研究的目的是评估鼻内镜下切除鼻窦血管肿瘤的有效性和安全性,并通过文献回顾评估不同亚型的疗效和临床行为。材料和方法:对鼻腔和眶尖血管瘤的患者进行回顾性分析。评估患者的人口统计学、手术方法、并发症、组织病理学结果和长期结果。结果:本研究包括22名患者。平均肿瘤大小为6至100毫米(30.45±22.7毫米)。组织病理学检查显示毛细血管瘤8例(36%),海绵状血管瘤6例(33.3%),混合性血管瘤2例(12%),血管平滑肌瘤2例(12%)。3例(13.6%)患者被诊断为肾小球上皮细胞瘤,其余1例(4.4%)为血管肉瘤。只有1例复发性肾小球上皮细胞瘤患者需要术前栓塞。五名患者在办公室进行了术前活检。平均随访72.9(±53.71)个月。复发3例(13.6%)。结论:经鼻内镜下鼻窦血管瘤切除术是一种安全可靠的方法。我们的研究表明,要实现完全切除,肿瘤的位置比大小更重要。长期随访对于早期发现复发很重要,即使在宏观上完全切除后也是如此。
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Experience with endonasal endoscopic resection of non-angiofibroma sinonasal and orbital apex vascular tumours
Background: Endoscopic endonasal approach for the management of sinonasal inflammatory pathologies and tumours has been a widely accepted procedure and used for many years. The aim of the study is to assess effectiveness and safety of endonasal endoscopic resection in removal of sinonasal vascular tumours and to evaluate outcomes and clinical behaviour of different subtypes with review of the literature. Material and Methods: A retrospective review of the patients treated for sinonasal and orbital apex vascular tumour was performed. Patient’s demographics, surgical approaches, complications, histopathological results, and long-term outcomes were evaluated. Results: Twenty-two patient included in this study. The mean tumour size ranged from 6 to 100 mm (30.45 ± 22.7 mm). Histopathological examination revealed 8 (36%) capillary hemangioma, 6 (33.3%) cavernous hemangioma, 2 (12%) mixed hemangioma, and 2(12%) vascular leiomyomas. Three (13.6%) patients were diagnosed as glomangiopericytoma and remaining 1 (4.4%) was angiosarcoma. Only in 1 patient with recurrent glomangiopericytoma preoperative embolization were needed. Five patients had preoperative biopsy in office settings. The mean follow-up was 72.9 (± 53.71) months. The recurrence was observed in 3 (13.6%) patients. Conclusion: Endonasal endoscopic approach for sinonasal vascular tumours is a safe and reliable method for resection. Our study suggested location of the tumour is more important than the size to achieve complete resection. Long-term follow-ups are important to detect recurrences early even after macroscopically complete resections.
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