血红蛋白不是生物芬顿试剂

Reactive oxygen species (Apex, N.C.) Pub Date : 2022-03-02 DOI:10.20455/ros.2022.c.801

P. Penketh

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摘要

据报道，血红蛋白是一种生物芬顿试剂，是羟基自由基氧化产生的结果。这些羟基自由基被认为是血红蛋白与过氧化氢反应产生的。然而，观察到的氧化实际上是由于强氧化性铁（IV）铁酰基物质的产生，而不是由于羟基自由基。（首次在线：2022年3月1日）

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Hemoglobin Is Not a Biological Fenton Reagent

Hemoglobin has been reported to be a biological Fenton reagent, as a consequence of oxidations believed to be produced by hydroxyl radicals. These hydroxyl radicals were thought to be generated from the reaction of hemoglobin with hydrogen peroxide. However, the oxidations that were observed were in fact due to the generation of a strongly oxidizing iron (IV) ferryl species, and not due to hydroxyl radicals. (First online: March 1, 2022)

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Reactive oxygen species (Apex, N.C.)

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