{"title":"龙葵的植物化学成分和药理潜力。，提取物：特别强调其美白皮肤、抗糖尿病、乙酰胆碱酯酶和基因毒性活性","authors":"Roktim Gogoi, Neelav Sarma, S. K. Pandey, M. Lal","doi":"10.30495/TPR.2021.1917249.1190","DOIUrl":null,"url":null,"abstract":"This study was designed to evaluate and compare the phytochemical constituents along with the bioactivities of Solanum khasianum C.B. Clarke. leaves (SKLME) and berries (SKBME) methanolic extracts. Alkaloids, flavonoids, saponins, steroids, terpenoids, phenols, oxalates and cardiac glycosides were present in SKLME and SKBME. Considerable amounts of phenolic and flavonoids were found in SKLME and SKBME. SKBME showed better antioxidant activity with an IC50 value of 20.68 μg/mL vs SKLME (38.30 μg/mL). SKBME and SKLME respectively showed anti-inflammatory activity with IC50 of 20.96 and 23.37 μg/mL. Apart from this, the present investigation also reports SKBME skin whitening ability, anti-diabetic potential and anti-cholinesterase activity with IC50 values of 33.97, 28.24, and 32.42 μg/mL, respectively. Furthermore, SKLME showed herbicidal property with a total germination rate of 9.06% at a concentration of 80 μg/mL. Bioactivity analysis revealed higher pharmacological importance of the SKBME than SKLME, as well.","PeriodicalId":47547,"journal":{"name":"TOWN PLANNING REVIEW","volume":"5 1","pages":"47-61"},"PeriodicalIF":1.6000,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":"{\"title\":\"Phytochemical constituents and pharmacological potential of Solanum khasianum C.B. Clarke., extracts: Special emphasis on its skin whitening, anti-diabetic, acetylcholinesterase and genotoxic activities\",\"authors\":\"Roktim Gogoi, Neelav Sarma, S. K. Pandey, M. Lal\",\"doi\":\"10.30495/TPR.2021.1917249.1190\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This study was designed to evaluate and compare the phytochemical constituents along with the bioactivities of Solanum khasianum C.B. Clarke. leaves (SKLME) and berries (SKBME) methanolic extracts. Alkaloids, flavonoids, saponins, steroids, terpenoids, phenols, oxalates and cardiac glycosides were present in SKLME and SKBME. Considerable amounts of phenolic and flavonoids were found in SKLME and SKBME. SKBME showed better antioxidant activity with an IC50 value of 20.68 μg/mL vs SKLME (38.30 μg/mL). SKBME and SKLME respectively showed anti-inflammatory activity with IC50 of 20.96 and 23.37 μg/mL. Apart from this, the present investigation also reports SKBME skin whitening ability, anti-diabetic potential and anti-cholinesterase activity with IC50 values of 33.97, 28.24, and 32.42 μg/mL, respectively. Furthermore, SKLME showed herbicidal property with a total germination rate of 9.06% at a concentration of 80 μg/mL. Bioactivity analysis revealed higher pharmacological importance of the SKBME than SKLME, as well.\",\"PeriodicalId\":47547,\"journal\":{\"name\":\"TOWN PLANNING REVIEW\",\"volume\":\"5 1\",\"pages\":\"47-61\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2021-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"TOWN PLANNING REVIEW\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.30495/TPR.2021.1917249.1190\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"URBAN STUDIES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"TOWN PLANNING REVIEW","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30495/TPR.2021.1917249.1190","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"URBAN STUDIES","Score":null,"Total":0}
Phytochemical constituents and pharmacological potential of Solanum khasianum C.B. Clarke., extracts: Special emphasis on its skin whitening, anti-diabetic, acetylcholinesterase and genotoxic activities
This study was designed to evaluate and compare the phytochemical constituents along with the bioactivities of Solanum khasianum C.B. Clarke. leaves (SKLME) and berries (SKBME) methanolic extracts. Alkaloids, flavonoids, saponins, steroids, terpenoids, phenols, oxalates and cardiac glycosides were present in SKLME and SKBME. Considerable amounts of phenolic and flavonoids were found in SKLME and SKBME. SKBME showed better antioxidant activity with an IC50 value of 20.68 μg/mL vs SKLME (38.30 μg/mL). SKBME and SKLME respectively showed anti-inflammatory activity with IC50 of 20.96 and 23.37 μg/mL. Apart from this, the present investigation also reports SKBME skin whitening ability, anti-diabetic potential and anti-cholinesterase activity with IC50 values of 33.97, 28.24, and 32.42 μg/mL, respectively. Furthermore, SKLME showed herbicidal property with a total germination rate of 9.06% at a concentration of 80 μg/mL. Bioactivity analysis revealed higher pharmacological importance of the SKBME than SKLME, as well.
期刊介绍：
Town Planning Review has been one of the world"s leading journals of urban and regional planning since its foundation in 1910. With an extensive international readership, TPR is a well established urban and regional planning journal, providing a principal forum for communication between researchers and students, policy analysts and practitioners. To mark TPR’s centenary in 2010, it is proposed to publish a series of ‘Centenary Papers’ -- review papers that record and reflect on the state of the art in a range of topics in the general field of town and regional planning.
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